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Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model
Kathleen A. Ashcraft et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2015)
Paraoxonase-2 (PON2) protects oral squamous cell cancer cells against irradiation-induced apoptosis
Maximilian Krueger et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2015)
Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo
Jun Jacob Hu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Peroxiredoxin 1 promotes tumorigenesis through regulating the activity of mTOR/p70S6K pathway in esophageal squamous cell carcinoma
Fanghua Gong et al.
MEDICAL ONCOLOGY (2015)
A historical overview of protein kinases and their targeted small molecule inhibitors
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2015)
Roles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis
Meiling Lu et al.
ONCOTARGETS AND THERAPY (2015)
Reactive oxygen species and p21Waf1/Cip1 are both essential for p53-mediated senescence of head and neck cancer cells
A. L. Fitzgerald et al.
CELL DEATH & DISEASE (2015)
Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells
Shu-Ting Pan et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2015)
Preparation of GST Inhibitor Nanoparticle Drug Delivery System and Its Reversal Effect on the Multidrug Resistance in Oral Carcinoma
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NANOMATERIALS (2015)
Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer
Victor D. Martinez et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2015)
Regulation of HIF-1 Alpha by the Proprotein Convertases Furin and PC7 in Human Squamous Carcinoma Cells
Jian Fu et al.
MOLECULAR CARCINOGENESIS (2015)
Redox- Modulated Phenomena and Radiation Therapy: The Central Role of Superoxide Dismutases
Aaron K. Holley et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Dichloroacetate and cancer: New home for an orphan drug?
Shyam Kankotia et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2014)
HIF-1 Signaling in Drug Resistance to Chemotherapy
N. A. Warfel et al.
CURRENT MEDICINAL CHEMISTRY (2014)
Collateral sensitivity: ABCG2-overexpressing cells are more vulnerable to oxidative stress
Damian Krzyanowski et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Effects of D-allose in combination with docetaxel in human head and neck cancer cells
Kanako Indo et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
New and emerging HDAC inhibitors for cancer treatment
Alison C. West et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Protective effects of Korean red ginseng against radiation-induced apoptosis in human HaCaT keratinocytes
Jae Won Chang et al.
JOURNAL OF RADIATION RESEARCH (2014)
Radioprotective effect of epicatechin in cultured human fibroblasts and zebrafish
Hyang Ae Shin et al.
JOURNAL OF RADIATION RESEARCH (2014)
Metformin-mode of action and clinical implications for diabetes and cancer
Ida Pernicova et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Elevated Expression of AKR1C3 Increases Resistance of Cancer Cells to Ionizing Radiation via Modulation of Oxidative Stress
Wei Xiong et al.
PLOS ONE (2014)
HDAC inhibitors reverse acquired radio resistance of KYSE-150R esophageal carcinoma cells by modulating Bmi-1 expression
Qinghua Dong et al.
TOXICOLOGY LETTERS (2014)
Clinical update on cancer: molecular oncology of head and neck cancer
Y. Suh et al.
CELL DEATH & DISEASE (2014)
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
Rajat Banerjee et al.
NATURE COMMUNICATIONS (2014)
Novel Resveratrol and 5-Fluorouracil Coencapsulated in PEGylated Nanoliposomes Improve Chemotherapeutic Efficacy of Combination against Head and Neck Squamous Cell Carcinoma
Aarti Mohan et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Nanomedicine therapeutic approaches to overcome cancer drug resistance
Janet L. Markman et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Oxidative stress and cancer: An overview
Venus Sosa et al.
AGEING RESEARCH REVIEWS (2013)
Role of Nrf2 in Oxidative Stress and Toxicity
Qiang Ma
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)
Glutathione and glutathione analogues; Therapeutic potentials
Jian Hui Wu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
ERCC1 is a prognostic biomarker in locally advanced head and neck cancer: results from a randomised, phase II trial
J. E. Bauman et al.
BRITISH JOURNAL OF CANCER (2013)
Cytotoxicity of lapachol, β-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells
Suthananda N. Sunassee et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
The emerging role of the Nrf2-Keap1 signaling pathway in cancer
Melba C. Jaramillo et al.
GENES & DEVELOPMENT (2013)
Could Radiotherapy Effectiveness Be Enhanced by Electromagnetic Field Treatment?
Artacho-Cordon Francisco et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells
Pei-Ying Chang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Aspirin Therapy
Janet M. Torpy et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria
Michaela Aichler et al.
JOURNAL OF PATHOLOGY (2013)
Modulation of EGFR and ROS induced cytochrome c release by combination of photodynamic therapy and carboplatin in human cultured head and neck cancer cells and tumor xenograft in nude mice
Heejun Hwang et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2013)
Cetuximab Reverses the Warburg Effect by Inhibiting HIF-1-Regulated LDH-A
Haiquan Lu et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Bortezomib and SAHA Synergistically Induce ROS-Driven Caspase-Dependent Apoptosis of Nasopharyngeal Carcinoma and Block Replication of Epstein-Barr Virus
Kwai Fung Hui et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma
Pengfei Ren et al.
ONCOLOGY REPORTS (2013)
Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells
Xiaoming Zhai et al.
ONCOLOGY REPORTS (2013)
Role of Glutathione in Cancer Progression and Chemoresistance
Nicola Traverso et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Effect of Epicatechin against Radiation-Induced Oral Mucositis: In Vitro and In Vivo Study
Yoo Seob Shin et al.
PLOS ONE (2013)
The chemopreventive and clinically used agent curcumin sensitizes HPV- but not HPV+ HNSCC to ionizing radiation, in vitro and in a mouse orthotopic model
Stephen W. Tuttle et al.
CANCER BIOLOGY & THERAPY (2012)
Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL
Daniel Nagel et al.
CANCER CELL (2012)
Chemical Insights into Ginseng as a Resource for Natural Antioxidants
Zai-Qun Liu
CHEMICAL REVIEWS (2012)
Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy
Tineke W. H. Meijer et al.
CLINICAL CANCER RESEARCH (2012)
Ten Years of Progress in Head and Neck Cancers
Shrujal Baxi et al.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2012)
HDAC inhibitor-based therapies: Can we interpret the code?
Maria New et al.
MOLECULAR ONCOLOGY (2012)
Individualized, multimodal palliative treatment of inoperable esophageal cancer: Clinical impact of photodynamic therapy resulting in prolonged survival
Joerg Lindenmann et al.
LASERS IN SURGERY AND MEDICINE (2012)
Susceptibility of Human Head and Neck Cancer Cells to Combined Inhibition of Glutathione and Thioredoxin Metabolism
Arya Sobhakumari et al.
PLOS ONE (2012)
Remarkable response to photodynamic therapy in residual T4N0M0 nasopharyngeal carcinoma: A case report
S. R. Indrasari et al.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2012)
Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems
Alexander R. Lippert et al.
ACCOUNTS OF CHEMICAL RESEARCH (2011)
Global Cancer Statistics
Ahmedin Jemal et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Enhancement of the radiation effects by D-allose in head and neck cancer cells
Hiroshi Hoshikawa et al.
CANCER LETTERS (2011)
GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response
Baishen Chen et al.
CANCER LETTERS (2011)
In Vivo Mapping of Hydrogen Peroxide and Oxidized Glutathione Reveals Chemical and Regional Specificity of Redox Homeostasis
Simone C. Albrecht et al.
CELL METABOLISM (2011)
Upregulation of thioredoxin reductase 1 in human oral squamous cell carcinoma
Shunichiro Iwasawa et al.
ONCOLOGY REPORTS (2011)
Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue
Xiaojie Zhu et al.
ORAL ONCOLOGY (2011)
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
Nicolas Stransky et al.
SCIENCE (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
The molecular biology of head and neck cancer
C. Rene Leemans et al.
NATURE REVIEWS CANCER (2011)
In Vitro and In Vivo Effects of D-Allose: Up-Regulation of Thioredoxin-Interacting Protein in Head and Neck Cancer Cells
Hiroshi Hoshikawa et al.
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY (2010)
Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies
Jenny Epstein et al.
BRITISH JOURNAL OF NUTRITION (2010)
Cancer Statistics, 2010
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CA-A CANCER JOURNAL FOR CLINICIANS (2010)
Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways
Ning Kang et al.
CANCER LETTERS (2010)
Flavanols and cardiovascular disease prevention
Christian Heiss et al.
EUROPEAN HEART JOURNAL (2010)
Induction of G2/M Phase Arrest and Apoptosis by Oridonin in Human Laryngeal Carcinoma Cells
Ning Kang et al.
JOURNAL OF NATURAL PRODUCTS (2010)
Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia
B. Rodriguez-Santiago et al.
MOLECULAR PSYCHIATRY (2010)
Head and neck cancer-Part 2: Treatment and prognostic factors
H. Mehanna et al.
BRITISH MEDICAL JOURNAL (2010)
Head and neck cancer-Part 1: Epidemiology, presentation, and prevention
H. Mehanna et al.
BMJ-BRITISH MEDICAL JOURNAL (2010)
Enhancement of cisplatin cytotoxicity by SAHA involves endoplasmic reticulum stress-mediated apoptosis in oral squamous cell carcinoma cells
Maiko Suzuki et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
Piyush B. Gupta et al.
CELL (2009)
The impact of flavonoids on memory: physiological and molecular considerations
Jeremy P. E. Spencer
CHEMICAL SOCIETY REVIEWS (2009)
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Maximilian Diehn et al.
NATURE (2009)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Prevalence of CYP1A1 and GST Polymorphisms in the Population of Northeastern India and Susceptibility of Oral Cancer
Sumana Chatterjee et al.
ONCOLOGY RESEARCH (2009)
Is photodynamic therapy a good alternative to surgery and radiotherapy in the treatment of head and neck cancer?
Heike J. Nyst et al.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2009)
Head and neck cancer - An evolving treatment paradigm
David M. Cognetti et al.
CANCER (2008)
Chemopreventive effects of natural dietary compounds on cancer development
Min-Hsiung Pan et al.
CHEMICAL SOCIETY REVIEWS (2008)
A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cells
Bryan C. Dickinson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Up-regulated manganese superoxide dismutase expression increases apoptosis resistance in human esophageal squamous cell carcinomas
Hu Hai et al.
CHINESE MEDICAL JOURNAL (2007)
Factors affecting drug concentrations and QT interval during thioridazine therapy
R. H. K. Thanacoody et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
Human manganese superoxide dismutase suppresses HER2/neu-mediated breast cancer malignancy
Tzu-Chao Chuang et al.
FEBS LETTERS (2007)
Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome
Ahsan M. Kaimul et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Design and synthesis of fluorescent probes for selective detection of highly reactive oxygen species in mitochondria of living cells
Yuichiro Koide et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
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Thioridazine for schizophrenia (Withdrawn Paper. 2007, art. no. CD001944)
M. Fenton et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2007)
Selective fluorescent imaging of superoxide in vivo using ethidium-based probes
Kristine M. Robinson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Genetically encoded fluorescent indicator for intracellular hydrogen peroxide
VV Belousov et al.
NATURE METHODS (2006)
Sensor/Effector drug design with potential relevance to cancer
Fiona H. Fry et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Mitochondrial manganese-superoxide dismutase expression in ovarian cancer
YM Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Molecular pathways in the chemosensitization of cisplatin by quercetin in human head and neck cancer
H Sharma et al.
CANCER BIOLOGY & THERAPY (2005)
Metformin and reduced risk of cancer in diabetic patients
JMM Evans et al.
BMJ-BRITISH MEDICAL JOURNAL (2005)
ROS stress in cancer cells and therapeutic implications
H Pelicano et al.
DRUG RESISTANCE UPDATES (2004)
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MEDICAL HYPOTHESES (2000)
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