期刊
ORGANIC LETTERS
卷 22, 期 15, 页码 5731-5736出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c01607
关键词
-
资金
- Iowa State University
- Iowa State University Center for Catalysis
The Ni-catalyzed carboacylation of alkynes with amide electrophiles and triarylboroxines is presented. The reaction generates all-carbon tetrasubstituted alkene products in up to 62% yield. NiCl2.glyme is used as an inexpensive precatalyst in the absence of any external reductant or exogenous ligand. Design of Experiment (DoE) was used to achieve the best combination of yield and stereoselectivity in this acylative carbodifunction-alization of alkynes to generate highly substituted enones.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据