期刊
ORGANIC LETTERS
卷 22, 期 15, 页码 6021-6025出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c02115
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资金
- Sanofi
The development of a copper-catalyzed cross-coupling between primary and secondary (pseudo)halides and bicyclopentyl Grignard reagents is reported. Highly strained bicyclopentanes can be cross-coupled with a large panel of primary alkyl mesylates and secondary alkyl iodides. The catalytic system is simple and cheap, and the reaction is general and chemoselective.
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