期刊
OCULAR IMMUNOLOGY AND INFLAMMATION
卷 29, 期 5, 页码 922-925出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/09273948.2019.1704027
关键词
Retinitis; infectious uveitis; encephalitis; pseudorabies virus; swine; next-generation sequencing
资金
- Capital Health Research and Development of Special
- Capital Medical University Affiliated Beijing Tongren Hospital Key Medical Development Plan [trzdyxzy201801]
This study reported a case of bilateral necrotizing retinitis following viral encephalitis caused by the pseudorabies virus. The patient was a 49-year-old male pig slaughterer. The findings emphasize the potential risk of pseudorabies virus causing retinitis among individuals with close contact to pigs.
Purpose: The objective of this study was to report a case of bilateral necrotizing retinitis following viral encephalitis caused by the pseudorabies virus. Case report: A 49-year-old male had decreased bilateral visual acuity after the recovery of consciousness for one month. He had been in an unconsciousness status due to encephalitis for two months before the ocular symptoms developed. He was a pig slaughterer. Ocular ultrasound showed bilateral vitreous haze and retinal detachment. A vitrectomy and silicone oil tamponade were performed on the left eye. During surgery, massive periphery retinal necrosis appearing as a tattered fish net, and multiple retinal holes were observed. The pseudorabies virus was detected by next-generation sequencing in the vitreous specimen. Conclusion: The pseudorabies virus may cause bilateral necrotizing retinitis following viral encephalitis among those with close contact to pigs. Intraocular fluid provides a greater selection of samples and a longer time window for pathogenic detection.
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