Prostate-Specific Membrane Antigen PET/CT Findings for Hepatic Hemangioma

We report a case of a benign liver hemangioma with intense prostate-specific membrane antigen (PSMA) uptake on Ga-68 PET/CT. A 77-year-old man with prostate adenocarcinoma underwent routine staging with PSMA PET/CT. This revealed an intensely PSMA-avid liver lesion. The known prostate adenocarcinoma was localized and had mild uptake. Diagnostic CT and MRI were characteristic of a hemangioma without interval growth over a 3-month period. PSMA PET/CT is becoming increasingly popular for staging in prostate cancer, and the presence of PSMA uptake in extra-prostatic tumors is being increasingly documented.