期刊
CLINICAL NUCLEAR MEDICINE
卷 41, 期 8, 页码 595-605出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000001228
关键词
fluorodeoxyglucose F18; positron-emission tomography; multi-detector computed tomography; malignant tumor; trachea
Purpose: Primary malignant tracheal tumors are rare, and their clinical presentation often resembles other diseases of the respiratory system. This study summarized F-18-FDG PET/CT and CE-CT findings on histologically confirmed primary malignant tracheal tumors in 13 patients. Materials and Methods: We retrospectively reviewed the F-18-FDG PET/CT and CE-CT findings of 13 patients with histologically confirmed primary tumors who had undergone PET/CT and CE-CT in the same session. The following parameters were recorded: SUVmax; SUVmax lesion/background; location, size and attenuation of the mass; mediastinal invasion; and the presence of metastases. Clinical data, bronchial endoscopy results, and surgical and histopathological findings were also collected. Results: Tracheal soft tissue lesions with increased F-18-FDG uptake were observed in all patients. Five squamous cell carcinomas, 5 adenoid cystic carcinomas, 2 adenocarcinomas, and 1 mucosa-associated lymphoid tumor were histopathologically observed. The maximum SUV of the malignant tracheal tumors ranged from 2.7 to 20.5 (mean +/- SD, 6.8 +/- 4.8; median, 5.7). All SUVmax lesion values were greater than 2.5. Homogeneous enhancement was observed in all lesions, with three exhibiting evident enhancement, nine demonstrating moderate enhancement, and one showing mild enhancement. Conclusions: The presence of a tracheal soft tissue mass with increased F-18-FDG uptake is highly suggestive of a malignant tracheal tumor. F-18-FDG PET/CT and CE-CT can clearly demonstrate such a tumor's function and anatomical characteristics.
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