期刊
NUTRITION REVIEWS
卷 79, 期 6, 页码 726-741出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/nutrit/nuaa038
关键词
emulsifier; exposure; food additive; inflammatory bowel disease; legislation; safety
资金
- Leona M. and Harry B. Helmsley Charitable Trust
The consumption of food additives has increased, particularly emulsifiers, with the rise of ultra-processed food intake. Research on the health effects of food additive emulsifiers is limited, and there are challenges in estimating exposure levels. Brand-specific databases for emulsifiers and longer-term human trials are needed for future research.
Food additive intakes have increased with the increase in ultra-processed food consumption. Food additive emulsifiers have received particular research attention in recent years due to preliminary evidence of adverse gastrointestinal and metabolic health effects. In this review, the use of emulsifiers as food additives is discussed, and the current estimations of exposure to, and safety of, emulsifiers are critically assessed. Food additive emulsifier research is complicated by heterogeneity in additives considered to be emulsifiers and labelling of them on foods globally. Major limitations exist in estimating food additive emulsifier exposure, relating predominantly to a lack of available food occurrence and concentration data. Development of brand-specific food additive emulsifier databases are crucial to accurately estimating emulsifier exposure. Current research on the health effects of food additive emulsifiers are limited to in vitro and murine studies and small, acute studies in humans, and future research should focus on controlled human trials of longer duration.
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