相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution
Karol Szlachta et al.
BMC GENOMICS (2020)
Pausing sites of RNA polymerase II on actively transcribed genes are enriched in DNA double-stranded breaks
Sandeep Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity
Nicholas Sciascia et al.
ELIFE (2020)
NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation
Roopesh Anand et al.
EMBO JOURNAL (2019)
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations
Gaetano Ivan Dellino et al.
NATURE GENETICS (2019)
Sequence and Nuclease Requirements for Breakage and Healing of a Structure-Forming (AT)n Sequence within Fragile Site FRA16D
Simran Kaushal et al.
CELL REPORTS (2019)
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations
Henrike Johanna Gothe et al.
MOLECULAR CELL (2019)
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity
Andres Canela et al.
MOLECULAR CELL (2019)
AT-dinucleotide rich sequences drive fragile site formation
Michal Irony-Tur Sinai et al.
NUCLEIC ACIDS RESEARCH (2019)
A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome
William H. Gittens et al.
NATURE COMMUNICATIONS (2019)
DNA fragility in the parallel evolution of pelvic reduction in stickleback fish
Kathleen T. Xie et al.
SCIENCE (2019)
Site-Specific Cleavage by Topoisomerase 2: A Mark of the Core Centromere
Walter E. Mills et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
DNA replication stress drives fragile site instability
Michal Irony-Tur Sinai et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2018)
Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes
Junhua Zhao et al.
CELL REPORTS (2018)
Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human
Karol Szlachta et al.
GENOME BIOLOGY (2018)
Transcription and DNA Damage: Holding Hands or Crossing Swords?
Giuseppina D'Alessandro et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription
Fernando Gomez-Herreros et al.
NATURE COMMUNICATIONS (2017)
BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks
Winston X. Yan et al.
NATURE COMMUNICATIONS (2017)
Effects of Replication and Transcription on DNA Structure-Related Genetic Instability
Guliang Wang et al.
GENES (2017)
Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome
Fedor Kouzine et al.
CELL SYSTEMS (2017)
Genome Organization Drives Chromosome Fragility
Andres Canela et al.
CELL (2017)
Endogenous DNA Damage as a Source of Genomic Instability in Cancer
Anthony Tubbs et al.
CELL (2017)
MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts
Tomas Aparicio et al.
JOURNAL OF CELL BIOLOGY (2016)
Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes
Nguyen Ngoc Hoa et al.
MOLECULAR CELL (2016)
Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts
Rajashree A. Deshpande et al.
MOLECULAR CELL (2016)
G-quadruplex structures mark human regulatory chromatin
Robert Hansel-Hertsch et al.
NATURE GENETICS (2016)
DSBCapture: in situ capture and sequencing of DNA breaks
Stefanie V. Lensing et al.
NATURE METHODS (2016)
Roles of eukaryotic topoisomerases in transcription, replication and genomic stability
Yves Pommier et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Deep sequencing of 10,000 human genomes
Amalio Telenti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells
Bjoern Schwer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Repair Pathway Choices and Consequences at the Double-Strand Break
Raphael Ceccaldi et al.
TRENDS IN CELL BIOLOGY (2016)
A mechanism for 1,4-Benzoquinone-induced genotoxicity
Mi Young Son et al.
ONCOTARGET (2016)
Palindrome-Mediated Translocations in Humans: A New Mechanistic Model for Gross Chromosomal Rearrangements
Hidehito Inagaki et al.
FRONTIERS IN GENETICS (2016)
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders
Liis Uuskula-Reimand et al.
GENOME BIOLOGY (2016)
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes
Ram Madabhushi et al.
CELL (2015)
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
Mihaela Pertea et al.
NATURE BIOTECHNOLOGY (2015)
HISAT: a fast spliced aligner with low memory requirements
Daehwan Kim et al.
NATURE METHODS (2015)
Topoisomerase II and leukemia
MaryJean Pendleton et al.
BONE MARROW NICHE, STEM CELLS, AND LEUKEMIA: IMPACT OF DRUGS, CHEMICALS, AND THE ENVIRONMENT (2014)
Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2.DNA and Top2.RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)
Rui Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
CtIP Maintains Stability at Common Fragile Sites and Inverted Repeats by End Resection-Independent Endonuclease Activity
Hailong Wang et al.
MOLECULAR CELL (2014)
Phytochemicals as anticancer and chemopreventive topoisomerase II poisons
Adam C. Ketron et al.
PHYTOCHEMISTRY REVIEWS (2014)
Defining a personal, allele-specific, and single-molecule long-read transcriptome
Hagen Tilgner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structure-specific endonucleases: guardians of fragile site stability
Sheroy Minocherhomji et al.
TRENDS IN CELL BIOLOGY (2014)
Analysis of the t(3;8) of hereditary renal cell carcinoma: a palindrome-mediated translocation
Takema Kato et al.
CANCER GENETICS (2014)
MUS81-EME2 Promotes Replication Fork Restart
Alessandra Pepe et al.
CELL REPORTS (2014)
Global Regulation of Promoter Melting in Naive Lymphocytes
Fedor Kouzine et al.
CELL (2013)
The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability
Jennifer M. Mason et al.
HUMAN MOLECULAR GENETICS (2013)
Role of DNA secondary structures in fragile site breakage along human chromosome 10
Laura W. Dillon et al.
HUMAN MOLECULAR GENETICS (2013)
Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D
Xing Lu et al.
MOLECULAR CANCER (2013)
A blooming resolvase at chromosomal fragile sites
Achille Pellicioli et al.
NATURE CELL BIOLOGY (2013)
ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis
Valeria Naim et al.
NATURE CELL BIOLOGY (2013)
MUS81 promotes common fragile site expression
Songmin Ying et al.
NATURE CELL BIOLOGY (2013)
DNA Topoisomerases Participate in Fragility of the Oncogene RET
Laura W. Dillon et al.
PLOS ONE (2013)
TDP2-Dependent Non-Homologous End-Joining Protects against Topoisomerase II-Induced DNA Breaks and Genome Instability in Cells and In Vivo
Fernando Gomez-Herreros et al.
PLOS GENETICS (2013)
Genome-Wide Screen Reveals Replication Pathway for Quasi-Palindrome Fragility Dependent on Homologous Recombination
Yu Zhang et al.
PLOS GENETICS (2013)
The Werner Syndrome Exonuclease Facilitates DNA Degradation and High Fidelity DNA Polymerization by Human DNA Polymerase δ
Ashwini S. Kamath-Loeb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA
Ka Cheong Lee et al.
BIOLOGY OPEN (2012)
ViennaRNA Package 2.0
Ronny Lorenz et al.
ALGORITHMS FOR MOLECULAR BIOLOGY (2011)
TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage
Zhihong Zeng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Non-B DNA-forming Sequences and WRN Deficiency Independently Increase the Frequency of Base Substitution in Human Cells
Albino Bacolla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
All tangled up: how cells direct, manage and exploit topoisomerase function
Seychelle M. Vos et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
Verena Quennet et al.
NUCLEIC ACIDS RESEARCH (2011)
Secondary structure formation and DNA instability at fragile site FRA16B
Allison A. Burrow et al.
NUCLEIC ACIDS RESEARCH (2010)
Rearrangements of the MLL Gene Are Influenced by DNA Secondary Structure, Potentially Mediated by Topoisomerase II Binding
Hongan Le et al.
GENES CHROMOSOMES & CANCER (2009)
A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage
Felipe Cortes Ledesma et al.
NATURE (2009)
Targeting DNA topoisomerase II in cancer chemotherapy
John L. Nitiss
NATURE REVIEWS CANCER (2009)
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair
Hyun-Min Kim et al.
EMBO JOURNAL (2008)
Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase II
Anette Thyssen Jonstrup et al.
NUCLEIC ACIDS RESEARCH (2008)
An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S-cerevisiae
Haihua Zhang et al.
MOLECULAR CELL (2007)
The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks
Vidhya Narayanan et al.
CELL (2006)
Topoisomerase II cleavage activity within the human D11Z1 and DXZ1 alpha-satellite arrays
JM Spence et al.
CHROMOSOME RESEARCH (2005)
Folate-sensitive fragile site FRA10A is due to an expansion of a CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein
T Sarafidou et al.
GENOMICS (2004)
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle
P Pichierri et al.
ONCOGENE (2003)
Slipped-strand DNAs formed by long (CAG).(CTG) repeats: slipped-out repeats and slip-out junctions
CE Pearson et al.
NUCLEIC ACIDS RESEARCH (2002)
In vivo site-directed mutagenesis using oligonucleotides
F Storici et al.
NATURE BIOTECHNOLOGY (2001)
分享论文
