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JOURNAL OF NUCLEAR MEDICINE (2013)
A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry
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JOURNAL OF NUCLEAR MEDICINE (2013)
64Cu-DOTA-Trastuzumab PET Imaging in Patients with HER2-Positive Breast Cancer
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JOURNAL OF NUCLEAR MEDICINE (2013)
Synthesis and Evaluation of 64Cu-Labeled Monomeric and Dimeric NGR Peptides for MicroPET Imaging of CD13 Receptor Expression
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MOLECULAR PHARMACEUTICS (2013)
First 18F-labeled ligand for PET imaging of uPAR: In vivo studies in human prostate cancer xenografts
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NUCLEAR MEDICINE AND BIOLOGY (2013)
PET imaging with 89Zr: From radiochemistry to the clinic
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NUCLEAR MEDICINE AND BIOLOGY (2013)
Synthesis of [18F]RGD-K5 by catalyzed [3+2] cycloaddition for imaging integrin αvβ3 expression in vivo
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NUCLEAR MEDICINE AND BIOLOGY (2013)
Pilot study of 68Ga-DOTA-F(ab′)2-trastuzumab in patients with breast cancer
Volkan Beylergil et al.
NUCLEAR MEDICINE COMMUNICATIONS (2013)
Expression of Somatostatin Receptor (SSTR) Subtypes (SSTR-1, 2A, 3, 4 and 5) in Neuroendocrine Tumors Using Real-time RT-PCR Method and Immunohistochemistry
Gou Mizutani et al.
ACTA HISTOCHEMICA ET CYTOCHEMICA (2012)
Intranasal delivery of biologics to the central nervous system
Jeffrey J. Lochhead et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
Recent trends in antibody-based oncologic imaging
Sukhwinder Kaur et al.
CANCER LETTERS (2012)
Ribosomal production and in vitro selection of natural product-like peptidomimetics: The FIT and RaPID systems
Christopher J. Hipolito et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2012)
Synthesis, Cu(II) complexation, 64Cu-labeling and biological evaluation of cross-bridged cyclam chelators with phosphonate pendant arms
Riccardo Ferdani et al.
DALTON TRANSACTIONS (2012)
Advances in Immuno-Positron Emission Tomography: Antibodies for Molecular Imaging in Oncology
Scott M. Knowles et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Evaluation of 64Cu Labeled GX1: A Phage Display Peptide Probe for PET Imaging of Tumor Vasculature
Kai Chen et al.
MOLECULAR IMAGING AND BIOLOGY (2012)
Correlation of the Ga-68-Bombesin Analog Ga-68-BZH3 with Receptors Expression in Gliomas as Measured by Quantitative Dynamic Positron Emission Tomography (dPET) and Gene Arrays
Ludwig G. Strauss et al.
MOLECULAR IMAGING AND BIOLOGY (2012)
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Ravid Straussman et al.
NATURE (2012)
One-step 18F-labeling of peptides for positron emission tomography imaging using the SiFA methodology
Carmen Waengler et al.
NATURE PROTOCOLS (2012)
Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)
Shinya Oishi et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2012)
Quantitative Analysis and Comparison Study of [18F]AlF-NOTA-PRGD2, [18F]FPPRGD2 and [68Ga]Ga-NOTA-PRGD2 Using a Reference Tissue Model
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PLOS ONE (2012)
THERANOSTICS: From Molecular Imaging Using Ga-68 Labeled Tracers and PET/CT to Personalized Radionuclide Therapy - The Bad Berka Experience
Richard P. Baum et al.
THERANOSTICS (2012)
Pretargeted immuno-PET of CEA-expressing intraperitoneal human colonic tumor xenografts: a new sensitive detection method
Rafke Schoffelen et al.
EJNMMI RESEARCH (2012)
Impact of microdosing clinical study - Why necessary and how useful?
Yuichi Sugiyama et al.
ADVANCED DRUG DELIVERY REVIEWS (2011)
Protein scaffold-based molecular probes for cancer molecular imaging
Zheng Miao et al.
AMINO ACIDS (2011)
High-Yielding Aqueous 18F-Labeling of Peptides via Al18F Chelation
Christopher A. D'Souza et al.
BIOCONJUGATE CHEMISTRY (2011)
Advantages of RGD peptides for directing cell association with biomaterials
Susan L. Bellis
BIOMATERIALS (2011)
Stoichiometry-focused F-18-labeling of alkyne-substituted oligodeoxynucleotides using azido([F-18]fluoromethyl)benzenes by Cu-catalyzed Huisgen reaction
Takeshi Kuboyama et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Pharmacokinetic Studies of 68Ga-Labeled Bombesin (68Ga-BZH3) and F-18 FDG PET in Patients With Recurrent Gliomas and Comparison to Grading Preliminary Results
Antonia Dimitrakopoulou-Strauss et al.
CLINICAL NUCLEAR MEDICINE (2011)
Strategies for extended serum half-life of protein therapeutics
Roland E. Kontermann
CURRENT OPINION IN BIOTECHNOLOGY (2011)
One-step radiosynthesis of 18F-AlF-NOTA-RGD2 for tumor angiogenesis PET imaging
Shuanglong Liu et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2011)
Advantages of mRNA display selections over other selection techniques for investigation of protein-protein interactions
Hui Wang et al.
EXPERT REVIEW OF PROTEOMICS (2011)
Antisense drug discovery and development
Tsuyoshi Yamamoto et al.
FUTURE MEDICINAL CHEMISTRY (2011)
124I-huA33 Antibody PET of Colorectal Cancer
Jorge A. Carrasquillo et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
Immuno-PET of Cancer: A Revival of Antibody Imaging
Otto C. Boerman et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
PET of CXCR4 Expression by a 68Ga-Labeled Highly Specific Targeted Contrast Agent
Eleni Gourni et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
PET Imaging of the Gastrointestinal Absorption of Orally Administered Drugs in Conscious and Anesthetized Rats
Shinji Yamashita et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
Developmental Changes in P-Glycoprotein Function in the Blood-Brain Barrier of Nonhuman Primates: PET Study with R-11C-Verapamil and 11C-Oseltamivir
Tadayuki Takashima et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
Monitoring Tumor Response to Antiangiogenic Sunitinib Therapy with 18F-Fluciclatide, an 18F-Labeled αvβ3-Integrin and αvβ5-Integrin Imaging Agent
Mark R. Battle et al.
JOURNAL OF NUCLEAR MEDICINE (2011)
PET Imaging of Hypoxia-Inducible Factor-1-Active Tumor Cells with Pretargeted Oxygen-Dependent Degradable Streptavidin and a Novel 18F-Labeled Biotin Derivative
Takashi Kudo et al.
MOLECULAR IMAGING AND BIOLOGY (2011)
Human Islet Cell MORF/cMORF Pretargeting in a Xenogeneic Murine Transplant Model
Guozheng Liu et al.
MOLECULAR PHARMACEUTICS (2011)
Functional Mutation of Multiple Solvent-Exposed Loops in the Ecballium elaterium Trypsin Inhibitor-II Cystine Knot Miniprotein
Richard H. Kimura et al.
PLOS ONE (2011)
68Ga-labeled DOTA-Peptides and 68Ga-labeled Radiopharmaceuticals for Positron Emission Tomography: Current Status of Research, Clinical Applications, and Future Perspectives
Wouter A. P. Breeman et al.
SEMINARS IN NUCLEAR MEDICINE (2011)
Target-specific delivery of peptide-based probes for PET imaging
Kai Chen et al.
ADVANCED DRUG DELIVERY REVIEWS (2010)
In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice
Raffaella Rossin et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Development of Double-Stranded siRNA Labeling Method Using Positron Emitter and Its In Vivo Trafficking Analyzed by Positron Emission Tomography
Kentaro Hatanaka et al.
BIOCONJUGATE CHEMISTRY (2010)
Improved 18F Labeling of Peptides with a Fluoride-Aluminum-Chelate Complex
William J. McBride et al.
BIOCONJUGATE CHEMISTRY (2010)
Phage display: Concept, innovations, applications and future
Jyoti Pande et al.
BIOTECHNOLOGY ADVANCES (2010)
Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans
Fiorella Petronzelli et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2010)
Adding a Clearing Agent to Pretargeting Does Not Lower the Tumor Accumulation of the Effector as Predicted
Guozheng Liu et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2010)
Immuno-Positron Emission Tomography: Shedding Light on Clinical Antibody Therapy
Guus A. M. S. van Dongen et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2010)
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
Thaddeus J. Wadas et al.
CHEMICAL REVIEWS (2010)
Biodistribution of 89Zr-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer
E. C. Dijkers et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Somatostatin receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors
Dik J. Kwekkeboom et al.
ENDOCRINE-RELATED CANCER (2010)
Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE
Irene Virgolini et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2010)
Prognostic relevance of tumour cell-associated uPAR expression in invasive ductal breast carcinoma
Matthias Kotzsch et al.
HISTOPATHOLOGY (2010)
Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography
Noriyasu Kamei et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumours, current aspects and new perspectives
Marialuisa Appetecchia et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2010)
Molecular Imaging of HER2-Expressing Malignant Tumors in Breast Cancer Patients Using Synthetic 111In- or 68Ga-Labeled Affibody Molecules
Richard P. Baum et al.
JOURNAL OF NUCLEAR MEDICINE (2010)
A Novel Facile Method of Labeling Octreotide with 18F-Fluorine
Peter Laverman et al.
JOURNAL OF NUCLEAR MEDICINE (2010)
Pretargeted Immuno-Positron Emission Tomography Imaging of Carcinoembryonic Antigen-Expressing Tumors with a Bispecific Antibody and a 68Ga- and 18F-Labeled Hapten Peptide in Mice with Human Tumor Xenografts
Rafke Schoffelen et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Affinity Enhancement Pretargeting: Synthesis and Testing of a 99mTc-Labeled Bivalent MORF
Jiang He et al.
MOLECULAR PHARMACEUTICS (2010)
Conformational Heterogeneity in PNA:PNA Duplexes
Filbert Totsingan et al.
MACROMOLECULES (2010)
MET signalling: principles and functions in development, organ regeneration and cancer
Livio Trusolino et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Regulation of cell signalling by uPAR
Harvey W. Smith et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Antibody Vectors for Imaging
Tove Olafsen et al.
SEMINARS IN NUCLEAR MEDICINE (2010)
Integrins in cancer: biological implications and therapeutic opportunities
Jay S. Desgrosellier et al.
NATURE REVIEWS CANCER (2010)
siRNA delivery systems for cancer treatment
Yu-Kyoung Oh et al.
ADVANCED DRUG DELIVERY REVIEWS (2009)
An Engineered Knottin Peptide Labeled with 18F for PET Imaging of Integrin Expression
Zheng Miao et al.
BIOCONJUGATE CHEMISTRY (2009)
Engineered Knottin Peptides: A New Class of Agents for Imaging Integrin Expression in Living Subjects
Richard H. Kimura et al.
CANCER RESEARCH (2009)
Use of a Novel Arg-Gly-Asp Radioligand, F-18-AH111585, to Determine Changes in Tumor Vascularity After Antitumor Therapy
Matthew S. Morrison et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Radiation Dosimetry of 89Zr-Labeled Chimeric Monoclonal Antibody U36 as Used for Immuno-PET in Head and Neck Cancer Patients
Pontus K. E. Boerjesson et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
On the Selection of a Tracer for PET Imaging of HER2-Expressing Tumors: Direct Comparison of a 124I-Labeled Affibody Molecule and Trastuzumab in a Murine Xenograft Model
Anna Orlova et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Imaging of integrin αvβ3 expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography
Oliver Schnell et al.
NEURO-ONCOLOGY (2009)
Adding L-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases
Takahito Mukai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
A Semiempirical Model of Tumor Pretargeting
Guozheng Liu et al.
BIOCONJUGATE CHEMISTRY (2008)
Radiosynthesis and biodistribution of cyclic RGD peptides conjugated with novel [18F]fluorinated aldehyde-containing prosthetic groups
Matthias Glaser et al.
BIOCONJUGATE CHEMISTRY (2008)
Convenient preparation of 68Ga-based PET-radiopharmaceuticals at room temperature
I. Velikyan et al.
BIOCONJUGATE CHEMISTRY (2008)
Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor-Activating Mutations
Seiji Yano et al.
CANCER RESEARCH (2008)
Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients
Laura M. Kenny et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Preparation of a promising angiogenesis PET imaging agent:: 68Ga-labeled c(RGDyK)-isothiocyanatobenzyl-1,4,7-triazacyclononane-1,4,7-triacetic acid and feasibility studies in mice
Jae Min Jeong et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide
Shigeru Kawakami et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Toward [18F]-labeled aryltrifluoroborate radiotracers:: In vivo positron emission tomography imaging of stable aryltrifluoroborate clearance in mice
Richard Ting et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Pretargeting CWR22 prostate tumor in mice with MORF-B72.3 antibody and radiolabeled cMORF
Guozheng Liu et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2008)
Multifunctional antibodies by the dock-and-lock method for improved cancer Imaging and therapy by pretargeting
David M. Goldenberg et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
A fully automated synthesis for the preparation of 68Ga-labelled peptides
Clemens Decristoforo et al.
NUCLEAR MEDICINE COMMUNICATIONS (2007)
68Ga-Labeled bombesin studies in patients with gastrointestinal stromal tumors:: Comparison with 18F-FDG
Antonia Dimitrakopoulou-Strauss et al.
JOURNAL OF NUCLEAR MEDICINE (2007)
Are radiogallium-labelled DOTA-conjugated somatostatin analogues superior to those labelled with other radiometals?
P. Antunes et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2007)
Application of LC-MS for quantitative analysis and metabolite identification of therapeutic oligonucleotides
Zhongping John Lin et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2007)
Immuno-PET: A navigator in monoclonal antibody development and applications
Guus A. M. S. van Dongen et al.
ONCOLOGIST (2007)
NC-100717: A versatile RGD peptide scaffold for angiogenesis imaging
Bard Indrevoll et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
The effect of β+ energy on performance of a small animal PET camera
M. Partridge et al.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT (2006)
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
Anne des Rieux et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin αvβ3 expression in man
Ambros J. Beer et al.
CLINICAL CANCER RESEARCH (2006)
Performance of immuno-positron emission tomography with zirconium-89-labeled chimeric monoclonal antibody U36 in the detection of lymph node metastases in head and neck cancer patients
PKE Börjesson et al.
CLINICAL CANCER RESEARCH (2006)
Synthesis of N-succinimidyl 4-[F-18] fluorobenzoate, an agent for labeling proteins and peptides with F-18
Ganesan Vaidyanathan et al.
NATURE PROTOCOLS (2006)
F-18-labeling of peptides by means of an organosilicon-based fluoride acceptor
Ralf Schirrmacher et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody
RM Sharkey et al.
NATURE MEDICINE (2005)
Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods
RM Sharkey et al.
CLINICAL CANCER RESEARCH (2005)
Quantification of raf antisense oligonucleotide (rafAON) in biological matrices by LC-MS/MS to support pharmacokinetics of a liposome-entrapped rafAON formulation
JL Johnson et al.
BIOMEDICAL CHROMATOGRAPHY (2005)
Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl) alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131
H Tamamura et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Pretargeting in tumored mice with radiolabeled morpholino oligomer showing low kidney uptake
GZ Liu et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2004)
[F-18]Galacto-RGD: Synthesis, radiolabeling, metabolic stability, and radiation dose estimates
R Haubner et al.
BIOCONJUGATE CHEMISTRY (2004)
DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals
D Wild et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2003)
Positron emission tomography microdosing:: a new concept with application in tracer and early clinical drug development
M Bergström et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2003)
mRNA display: ligand discovery, interaction analysis and beyond
TT Takahashi et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries
N Fujii et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells
K Sakamoto et al.
NUCLEIC ACIDS RESEARCH (2002)
PET for in vivo pharmacokinetic and pharmacodynamic measurements
N Gupta et al.
EUROPEAN JOURNAL OF CANCER (2002)
Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand
JP Xiong et al.
SCIENCE (2002)
Pretargeted adjuvant radioimmunotherapy with Yttrium-90-biotin in malignant glioma patients: A pilot study
C Grana et al.
BRITISH JOURNAL OF CANCER (2002)
Peptide-derived antagonists of the urokinase receptor.: Affinity maturation by combinatorial chemistry, identification of functional epitopes, and inhibitory effect on cancer cell intravasation
M Ploug et al.
BIOCHEMISTRY (2001)
Pretargeting with amplification using polymeric peptide nucleic acid
Y Wang et al.
BIOCONJUGATE CHEMISTRY (2001)
Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands
JC Reubi et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE (2001)
Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicity
DB Axworthy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Pretargeted radioimmunotherapy (PRIT™) for treatment of non-Hodgkin's lymphoma (NHL):: Initial phase I/II study results
PL Weiden et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2000)
Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use
JC Reubi et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE (2000)