期刊
NEUROSURGERY CLINICS OF NORTH AMERICA
卷 31, 期 3, 页码 395-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nec.2020.03.004
关键词
Epilepsy surgery; MRI; Networks; Surgical planning
资金
- CIHR [MOP-123520, MOP-57840]
- Natural Sciences and Research Council (NSERC) [243141, 24779]
- Epilepsy Canada Jay and Aiden Barker grant [247394]
- Canada First Research Excellence Fund [HBHL-1a-5a-06]
- German Research Foundation [DFG FO996/1-1]
Continuing advancements in neuroimaging methodology allow for increasingly detailed in vivo characterization of structural and functional brain networks, leading to the recognition of epilepsy as a disorder of large-scale networks. In surgical candidates, analysis of functional networks has proved invaluable for the identification of eloquent brain areas, such as hemispherical language dominance. More recently, connectome-based biomarkers have demonstrated potential to further inform clinical decision making in drug-refractory epilepsy. This article summarizes current evidence on epilepsy as a network disorder, emphasizing potential benefits of network analysis techniques for preoperative assessments and resection planning.
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