A new ceramide from the leaves ofLannea schimperi(Hochst. ex A.Rich.) Engl.

A new ceramide is being reported herein together with six known compounds from the methanol extract of the leaves ofLannea schimperi(Hochst. ex A.Rich.) Engl. The metabolites were obtained through repeated open column chromatography and were characterized by spectroscopic and spectrometric techniques. The radical-scavenging activity of the crude extract and isolated compounds was evaluated using the DPPH radical. The obtained results suggest the studied species as prominent candidate to fight reactive oxygen species (ROS).

Automated summary

This study reports a new ceramide and six known compounds from the methanol extract of Lannea schimperi leaves. These metabolites were characterized using spectroscopic and spectrometric techniques and demonstrated promising radical-scavenging activity against reactive oxygen species (ROS).