期刊
MOLECULES
卷 25, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/molecules25112653
关键词
oxidative stress; blood; pharmacological target; antioxidant supplementation; disease prevention; disease therapy; miRNAs
Oxidative stress (OxS) is one of the main processes related to aging and a common denominator of many different chronic/degenerative diseases (e.g., cardiovascular and neurodegenerative conditions and cancer). Thus, its potential modulation by supplementation/pharmacological therapy caused a lot of interest. However, these expectations have been mitigated by the obtainment of controversial results (beneficial, null, or adverse effects) following antioxidant interventions. Here, we discuss the current understanding of OxS assessment in health and disease, challenges and the potential of its evaluation in clinical practice, and available and future development for supplementation and pharmacologic strategies targeting OxS.
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