Advances in Research on the Preparation and Biological Activity of Maslinic Acid

Maslinic acid, a pentacyclic triterpene acid, is mainly isolated from olives. Maslinic acid and its derivatives exhibit a broad range of biological properties, such as anti-inflammatory, anti-cancer, anti-diabetic, antimicrobial, neuroprotective and hepatoprotective activities. In this mini-review, the progress of research on maslinic acid with regard to its bioactivities, extraction, semi-synthetic preparation and patents is reported. The relationships between the structure and the activity of maslinic acid and its derivatives are also discussed.

Automated summary

Maslinic acid, a pentacyclic triterpene acid primarily found in olives, demonstrates a wide range of biological properties including anti-inflammatory, anti-cancer, anti-diabetic, antimicrobial, neuroprotective, and hepatoprotective activities. This mini-review highlights the research progress on maslinic acid focusing on its bioactivities, extraction, semi-synthetic preparation, patents, and the structure-activity relationships of maslinic acid and its derivatives.