期刊
MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS
卷 26, 期 11, 页码 3501-3516出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00542-020-04946-y
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资金
- Ministry of Science and Technology, Taiwan [MOST 106-2634-F-009-001 CC2, MOST 107-2221-E-009 -166 -MY2, MOST 107-2218-E-009 006 -, MOST107-3017-F-009-003, MOST 107-2622-E-009 -025 CC2, MOST 108-2823-8-009 -002 -, MOST 108-2623-E-009 -004 D, MOST 109-2622-8-009-018 -TE1]
- Center for Intelligent Drug Systems and Smart Biodevices (IDS2 B)'' from The Featured Areas Research Center Program within Ministry of Education (MOE) in Taiwan
- Hsinchu Science Park Bureau, MOST grant [108A31B]
A fast digital chip is designed and fabricated successfully to implement the algorithm for estimating blood pressure (BP) in real time by a non-invasive cuffless photoplethysmogram (PPG) Sensor. The fast response accomplished by this digital computation chip is made possible by one-time calibration only and the Taiwan Semiconductor Manufacturing (TSMC) T18 process to realize the chip in an area of 3.97 mm(2). The experimental result shows that the overall power consumption of the chip is 15.62 mW. Finally, the blood pressure measurement platform has been developed with a user interface (UI) for long-term continuous cuffless BP measurement. The non-invasive blood pressure sensor is applied to the wrist arteries of 44 subjects for sensing the PPG pulsation of the blood vessel, and then estimating BPs (blood pressures). Measurement results shows that the maximum error in the BP measurement is +/- 6 mmHg. Which is less than 8 mmHg, defined by the Advancement of Medical Instrumentation (AAMI) and British Hypertension Society (BHS) standard.
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