Aptasensors as promising new tools in bisphenol A detection - An invisible pollution in food and environment

Owing to the endocrine disrupting effect, the detection of bisphenol A (BPA) is essential. Up to now, different chromatographic and spectroscopic analytical techniques have been developed for the detection of BPA, yet they are time-consuming, laborious and expensive. As a result, the development of a sensitive, specific and executive detection method seems vital. Recently, aptamers has been used as bioprobes of biosensors in a variety of targets. Much hopeful advancement in BPA aptasensors are being developed towards applications in food safety and environmental monitoring. In order to place these developments in outlook, this comprehensive review intends to present an overview on recent developed aptamer-based biosensors for the detection of BPA. Out of this review, trends in the development of colorimetric, fluorescence and electrochemical aptasensors for the monitoring of BPA are shown so that they will give a new idea for designing commercial kits. Finally, positive and negative points of each system are presented.