期刊
MICROBIAL PATHOGENESIS
卷 144, 期 -, 页码 -出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micpath.2020.104178
关键词
Sulfur nanoparticles; Elemental sulfur; Sodium thiosulfate; Sodium metabisulfite; Antimicrobial activity
资金
- National Research Foundation of Korea (NRF) - Korea government (MSIT) [2019R1A2C2084221]
- National Research Foundation of Korea [2019R1A2C2084221] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The antimicrobial activity of sulfur nanoparticles (SNPs) was compared with elemental sulfur and sulfur-containing salts (sodium thiosulfate and sodium metabisulfite) against bacteria (Escherichia coli, Staphylococcus aureus) and fungi (Aspergillus flavus, Candida albicans) using the paper disc, broth microdilution, and time-kill assay methods. The results of the paper disc and MIC tests showed stronger antimicrobial activity of SNPs compared to the elemental sulfur and sulfur-containing salts. SNPs showed more potent activity against bacteria than fungi. Among the test microorganisms, E. coli. (Gram-negative) was the most susceptible to SNPs, followed by S. aureus (Gram-positive), C. albicans (yeast), and A. flavus (mold). Scanning electron micrographs of microorganisms treated with SNPs showed different cell disruption patterns depending on the type of microorganisms.
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