期刊
CLINICAL NEPHROLOGY
卷 85, 期 4, 页码 238-244出版社
DUSTRI-VERLAG DR KARL FEISTLE
DOI: 10.5414/CN108694
关键词
human parvovirus B19; nephritic syndrome; acute glomerulonephritis; endocapillary glomerulonephritis; hypocomplementemia
A previously healthy 32-year-old woman developed arterial hypertension, proteinuria, and hematuria (nephritic syndrome) with normal renal function and was diagnosed with post-infectious glomerulonephritis secondary to parvovirus B19 infection. The renal biopsy showed endocapillary glomerulonephritis, with positive IgG, C3, and C1q immunoreactivity in the capillary walls and ultrastructural evidence of subendothelial deposits. The diagnosis of parvovirus B19 infection was confirmed by IgG/IgM serological positivity and parvovirus DNA demonstration in both peripheral blood and kidney tissue. Glomerular involvement improved spontaneously. To be noted are the atypical signs and symptoms of our patient who, unlike previously reported cases, failed to show fever, skin rash, or affected relatives.
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