相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Early antiretroviral therapy-treated perinatally HIV-infected seronegative children demonstrate distinct long-term persistence of HIV-specific T-cell and B-cell memory
Nicola Cotugno et al.
AIDS (2020)
The HIV-1 antibody response: a footprint of the viral reservoir in children vertically infected with HIV
Paolo Palma et al.
Lancet HIV (2020)
A Quantitative System for Monitoring Blood-Circulating Viral Protein R of Human Immunodeficiency Virus-1 Detected a Possible Link with Pathogenic Indices
Akihiro Matsunaga et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2019)
Viral protein R inhibitors from Swertia chirata of Myanmar
So-Yeun Woo et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2019)
Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection
Edward J. D. Greenwood et al.
CELL REPORTS (2019)
Influenza vaccination for HIV-positive people: Systematic review and network meta-analysis
Wei Zhang et al.
VACCINE (2018)
HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation
Manmeet K. Mamik et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2017)
The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention
Maria Eugenia Gonzalez
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging
Ying Wang et al.
NEUROPHARMACOLOGY (2017)
Isopimarane diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their Vpr inhibitory activity
Nwet Nwet Win et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages
Hichem Lahouassa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability
Georgia Rose Kafer et al.
CELL REPORTS (2016)
Distinct promoter activation mechanisms modulate noise-driven HIV gene expression
Arvind K. Chavali et al.
SCIENTIFIC REPORTS (2015)
Viral mechanisms of adipose dysfunction: lessons from HIV-1 Vpr
N. Agarwal et al.
ADIPOCYTE (2015)
Short Communication: Circulating Plasma HIV-1 Viral Protein R in Dual HIV-1/Tuberculosis Infection
Zahra Toossi et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2014)
Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing
Nadine Laguette et al.
CELL (2014)
Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors
Yi Hui et al.
EXPERIMENTAL CELL RESEARCH (2014)
Opinion: uracil DNA glycosylase (UNG) plays distinct and non-canonical roles in somatic hypermutation and class switch recombination
Ashraf S. Yousif et al.
INTERNATIONAL IMMUNOLOGY (2014)
Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals
Lela Kardava et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
HIV-1 Vpr Redirects Host Ubiquitination Pathway
Sakshi Arora et al.
JOURNAL OF VIROLOGY (2014)
Somatic Hypermutation at A/T-Rich Oligonucleotide Substrates Shows Different Strand Polarities in Ung-Deficient or -Proficient Backgrounds
Marija Zivojnovic et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification
Anders Wallenius et al.
MOLECULAR IMMUNOLOGY (2014)
Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA
Patrick Eldin et al.
NUCLEIC ACIDS RESEARCH (2014)
Expression and purification of soluble HIV-2 viral protein R (Vpr) using a sandwich-fusion protein strategy
Karen Haenel et al.
PROTEIN EXPRESSION AND PURIFICATION (2014)
HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1
Ruikang Liu et al.
RETROVIROLOGY (2014)
Influenza vaccination in HIV-infected individuals: Systematic review and assessment of quality of evidence related to vaccine efficacy, effectiveness and safety
Cornelius Remschmidt et al.
VACCINE (2014)
Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND)
Vasudev R. Rao et al.
AIDS RESEARCH AND THERAPY (2014)
HIV-1 Vpr-a still enigmatic multitasker
Carolin A. Guenzel et al.
FRONTIERS IN MICROBIOLOGY (2014)
Impairment of B-cell functions during HIV-1 infection
Sylvie Amu et al.
AIDS (2013)
A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported
Anastasia Galashevskaya et al.
DNA REPAIR (2013)
Separation of Function between Isotype Switching and Affinity Maturation In Vivo during Acute Immune Responses and Circulating Autoantibodies in UNG-Deficient Mice
Astrid Zahn et al.
JOURNAL OF IMMUNOLOGY (2013)
Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival
Adriano Ferrucci et al.
JOURNAL OF NEUROVIROLOGY (2013)
Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination
Tonika Lam et al.
PLOS ONE (2013)
Viral protein R of human immunodeficiency virus type-1 induces retrotransposition of long interspersed element-1
Kenta Iijima et al.
RETROVIROLOGY (2013)
HIV-1 Vpr Induces Adipose Dysfunction in Vivo Through Reciprocal Effects on PPAR/GR Co-Regulation
Neeti Agarwal et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Base Excision Repair
Hans E. Krokan et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
UNG shapes the specificity of AID-induced somatic hypermutation
Pablo Perez-Duran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
The HIV1 Protein Vpr Acts to Enhance Constitutive DCAF1-Dependent UNG2 Turnover
Xiaoyun Wen et al.
PLOS ONE (2012)
AID-Driven Deletion Causes Immunoglobulin Heavy Chain Locus Suicide Recombination in B Cells
Sophie Peron et al.
SCIENCE (2012)
Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir
Adriano Ferrucci et al.
VIRUS RESEARCH (2012)
Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase
Bizhan Romani et al.
CURRENT OPINION IN VIROLOGY (2012)
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity SPECIES DIFFERENCES BETWEEN MAN AND MOUSE
Berit Doseth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions
Robert W. Maul et al.
NATURE IMMUNOLOGY (2011)
The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase
Laurieann Casey et al.
CYTOKINE (2010)
HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation
Jinwoo Ahn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Stochastic gene expression as a molecular switch for viral latency
Abhyudai Singh et al.
CURRENT OPINION IN MICROBIOLOGY (2009)
Uracil DNA Glycosylase 2 negatively regulates HIV-1 LTR transcription
David Fenard et al.
NUCLEIC ACIDS RESEARCH (2009)
CD27- B-Cells Produce Class Switched and Somatically Hyper-Mutated Antibodies during Chronic HIV-1 Infection
Alberto Cagigi et al.
PLOS ONE (2009)
Mechanism and regulation of class switch recombination
Janet Stavnezer et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
Mutagenic roles of DNA repair proteins in antibody diversity and disease-associated trinucleotide repeat instability
Meghan M. Slean et al.
DNA REPAIR (2008)
Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 vpr from proteasomal degradation
Erwann Le Rouzic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
Susan Moir et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease
Susan Moir et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
A memoir of AID, which engraves antibody memory on DNA
Tasuku Honjo
NATURE IMMUNOLOGY (2008)
The immune geography of IgA induction and function
A. J. Macpherson et al.
MUCOSAL IMMUNOLOGY (2008)
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle
Kasia Hrecka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
HIV-I Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system
Jason L. DeHart et al.
VIROLOGY JOURNAL (2007)
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1
Baerbel Schroefelbauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Vpr in plasma of HIV type 1-positive patients is correlated with the HIV type 1 RNA titers
Shigeki Hoshino et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2007)
HIV-1 Vpr induces ATM-dependent cellular signal with enhanced homologous recombination
C. Nakai-Murakami et al.
ONCOGENE (2007)
HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E-coli by a similar mechanism of action
Mariana Santa-Marta et al.
MOLECULAR IMMUNOLOGY (2007)
Regulation of aicda expression and AID activity: Relevance to somatic Hypermutation and class switch DNA recombination
Zhenming Xu et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2007)
Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection
Kehmia Titanji et al.
BLOOD (2006)
Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells
XG Qiao et al.
NATURE IMMUNOLOGY (2006)
Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations
H Saribasak et al.
JOURNAL OF IMMUNOLOGY (2006)
Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions
L Li et al.
CELL RESEARCH (2005)
Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases
B Schröfelbauer et al.
JOURNAL OF VIROLOGY (2005)
HIV viral protein R causes atrial cardiomyocyte mitosis, mesenchymal tumor, dysrhythmia, and heart failure
W Lewis et al.
LABORATORY INVESTIGATION (2005)
Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection
A De Milito et al.
BLOOD (2004)
Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors
CO James et al.
JOURNAL OF VIROLOGY (2004)
The stoichiometry of Gag protein in HIV-1
JAG Briggs et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R
M Roshal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The cationic amphipathic α-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells
E Coeytaux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mechanism of HIV-1 viral protein R-induced apoptosis
K Muthumani et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
C Rada et al.
CURRENT BIOLOGY (2002)
HIV-1 Vpr displays natural protein-transducing properties: Implications for viral pathogenesis
MP Sherman et al.
VIROLOGY (2002)
Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest
P Henklein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The interaction of Vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 in vivo mutation rate
LM Mansky et al.
JOURNAL OF VIROLOGY (2000)
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
M Muramatsu et al.
CELL (2000)
分享论文
