4.2 Article

Synthesis and evaluation of biological activity of novel chromeno[4,3-b]quinolin-6-one derivatives by SO3H-tryptamine supported on Fe3O4@SiO2@CPS as recyclable and bioactive magnetic nanocatalyst

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JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
卷 17, 期 12, 页码 3271-3284

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SPRINGER
DOI: 10.1007/s13738-020-01990-3

关键词

Antimicrobial activity; Antioxidant activity; Bioactive magnetic nanocatalyst; Chromeno[4; 3-b]quinolin; SO3H supported on magnetic nanomaterials

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New derivatives of chromeno[4,3-b]quinolin-6-one were synthesized using novel SO3H-tryptamine supported on Fe3O4@SiO2@CPS which could be recycled as an effective magnetic nanocatalyst. SEM, EDX, XRD, FT-IR, TGA, VSM and BET analyses were utilized to confirm the magnetic nanocatalyst structure. Evaluation of Antimicrobial (antibacterial and antifungal) function of magnetic nanocatalyst as well as derivatives undergone synthesis was carried out according to MIC, MBC and MFC values. Moreover, evaluation of the derivatives subject to synthesis was performed according to DPPH free radical besides the biological features, in order to obtain justifiable biological features. [GRAPHICS] .

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