期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 142, 期 36, 页码 15569-15574出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.0c07273
关键词
-
资金
- National Natural Science Foundation of China [21675151, 21705145, 21721003]
- Ministry of Science and Technology of China [2016YFA0203203]
Despite the extensive studies of the nanozymes showing their superior properties compared to natural enzymes and traditional artificial enzymes, the development of highly specific nanozymes is still a challenge. The catechol oxidase specifically catalyzing the oxidations of o-diphenol to the corresponding o-quinone is important to the biosynthesis of melanin and other polyphenolic natural products. In this study, we first propose that MOF-818, containing trinuclear copper centers mimicking the active sites of natural catechol oxidase, shows efficient catechol oxidase activity with good specificity and no peroxidase-like characteristics. MOF-818 has good specificity and high catalytic activity as a novel catechol oxidase nanozyme.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据