期刊
JOURNAL OF NEUROPHYSIOLOGY
卷 124, 期 2, 页码 309-311出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/jn.00323.2020
关键词
dopamine; neuropeptides; reward; ventral tegmental area
资金
- Stanford Medical Scholars Fellowship Program
The role dopamine plays in reward-related behaviors has been debated for decades. Heymann et al. (Heymann G, Jo YS. Reichard KL, McFarland N. Chavkin C. Pahniter RD. Soden ME, Zweifel LS. Neuron 105: 909-920, 2020) identify subpopulations of dopamine-producing neurons that separately mediate reward association and motivation. Their results help demonstrate that dopamine signaling may partake in both reinforcement learning and incentive salience functions, instantiated by neuropeptide-defined subpopulations of the ventral tegmental area with different projection targets.
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