Synthesis, spectral, structural and antibacterial studies of ONO donor aroylhydrazone and its Mo(VI) complex

A tridentate ONO donor aroylhydrazone, 30,50-dichloro-20-hydroxyacetophenone-3-methoxybenzoylhydrazone monohydrate (H2CAB$ H2O) and its cis-MoO2 complex [MoO2(CAB)(DMF)] 2 (DMF) (1) have been synthesized and characterized by elemental analysis, LCMS, FT-IR, UVeVis and 1H NMR. The molecular structures were confirmed by single crystal X-ray diffraction studies. H2CAB$H2O and 1 got crystallized in a triclinic space group P1 as monohydrated and DMF solvated respectively. The asymmetric unit of complex 1 contains two complex molecules. All the synthesized compounds are subjected to in vitro antibacterial studies against a series of selected bacterial strains, by agar well diffusion method, using ampicillin as standard. Both the compounds are more active against Escherichia coli. (c) 2020 Elsevier B.V. All rights reserved.