期刊
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
卷 35, 期 14, 页码 2695-2702出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14767058.2020.1797666
关键词
Body composition; gestational diabetes mellitus; bioelectrical impedance analysis
资金
- National Natural Science Foundation of China [81701477, 81771607, 81571453, 81871185]
- 111 Project
This study identified that visceral fat levels, bone minerals, and percent body fat measured before 17 weeks gestation were significantly associated with an increased risk of gestational diabetes mellitus (GDM) in Chinese pregnant women.
Objectives This study aimed to identify which element of body composition measurements taken before 17th week gestation was the strongest risk factor for gestational diabetes mellitus (GDM) in Chinese pregnant women. Design and setting A retrospective study was performed using data retrieved from the Electronic Medical Record database of Chongqing Health Center for Women and Children (China) from January 2014 to December 2015. Participants A total of 22,223 women were included with singleton pregnancies and no preexisting diabetes who underwent bioelectrical impedance analysis (BIA) before 17 gestational weeks and 75-g OGTT at 24-28 gestational weeks. Results The prevalence of GDM from 2014 to 2015 was 27.13% (IADPSG). All indicators of BIA (total body water, fat mass, fat-free mass, percent body fat, muscle mass, visceral fat levels, proteins, bone minerals, basal metabolic rate, lean trunk mass), age, weight and body mass index (BMI) were risk factors that significantly increased the occurrence of GDM (p < .001 for all). Women older than 30 years or with a BMI more than 23, had a significantly higher GDM prevalence (34.89% and 34.77%). After adjusted covariates, visceral fat levels at the third quartile, theORsof GDM were 1.142 (95%CI1.032-1.263) in model I and 1.419 (95%CI1.274-1.581) in model II used the first quartile as reference (p < .05 for both); bone minerals at the third quartile, theORsof GDM were 1.124 (95%CI1.020-1.238) in model I and 1.311 (95%CI1.192-1.442) in model II (p < .05 for both). After adjusted for age, visceral fat levels and bone minerals,ORof GDM for percent body fat more than 28.77% at the third quartile was 1.334 (95%CI1.201-1.482) in model II (p < .05 for both). Conclusions Visceral fat levels, bone minerals and percent body fat were significantly associated with an increased risk of GDM, providing the reference ranges of visceral fat levels, bone minerals and percent body fat as predictive factors for Chinese women to estimate the risk of GDM by BIA during pregnancy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据