相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Cannabis glandular trichomes alter morphology and metabolite content during flower maturation
Samuel J. Livingston et al.
PLANT JOURNAL (2020)
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2020)
A yeast platform for high-level synthesis of tetrahydroisoquinoline alkaloids
Michael E. Pyne et al.
NATURE COMMUNICATIONS (2020)
Metabolic engineering and synthetic biology of plant natural products - A minireview
Aaron S. Birchfield et al.
CURRENT PLANT BIOLOGY (2020)
Advanced Strategies for Production of Natural Products in Yeast
Ruibing Chen et al.
ISCIENCE (2020)
Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus
Yang Qu et al.
PLANT JOURNAL (2019)
Complete biosynthesis of cannabinoids and their unnatural analogues in yeast
Xiaozhou Luo et al.
NATURE (2019)
Neopinone isomerase is involved in codeine and morphine biosynthesis in opium poppy
Mehran Dastmalchi et al.
NATURE CHEMICAL BIOLOGY (2019)
Synthetic biology strategies for microbial biosynthesis of plant natural products
Aaron Cravens et al.
NATURE COMMUNICATIONS (2019)
Purine Permease-Type Benzylisoquinoline Alkaloid Transporters in Opium Poppy
Mehran Dastmalchi et al.
PLANT PHYSIOLOGY (2019)
Structure-function studies of tetrahydroprotoberberine N-methyltransferase reveal the molecular basis of stereoselective substrate recognition
Dean E. Lang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Benzylisoquinoline alkaloid biosynthesis in opium poppy: an update
Aparna Singh et al.
PHYTOCHEMISTRY REVIEWS (2019)
A physical and genetic map of Cannabis sativa identifies extensive rearrangements at the THC/CBD acid synthase loci
Kaitlin U. Laverty et al.
GENOME RESEARCH (2019)
Engineering Plant Secondary Metabolism in Microbial Systems
Michael E. Pyne et al.
PLANT PHYSIOLOGY (2019)
Geissoschizine synthase controls flux in the formation of monoterpenoid indole alkaloids in a Catharanthus roseus mutant
Yang Qu et al.
PLANTA (2018)
Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase
Matthew R. Bennett et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead
Emanuela Martino et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Crystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway
Anna Kluza et al.
JOURNAL OF STRUCTURAL BIOLOGY (2018)
A pathogenesis-related 10 protein catalyzes the final step in thebaine biosynthesis
Xue Chen et al.
NATURE CHEMICAL BIOLOGY (2018)
Codeinone reductase isoforms with differential stability, efficiency and product selectivity in opium poppy
Mehran Dastmalchi et al.
PLANT JOURNAL (2018)
Solution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19E-geissoschizine
Yang Qu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Complete biosynthesis of noscapine and halogenated alkaloids in yeast
Yanran Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle
Lorenzo Caputi et al.
SCIENCE (2018)
Industrial brewing yeast engineered for the production of primary flavor determinants in hopped beer
Charles M. Denby et al.
NATURE COMMUNICATIONS (2018)
Microbial production of novel sulphated alkaloids for drug discovery
Eitaro Matsumura et al.
SCIENTIFIC REPORTS (2018)
Laboratory-scale production of (S)-reticuline, an important intermediate of benzylisoquinoline alkaloids, using a bacterial-based method
Eitaro Matsumura et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2017)
Engineering yeasts as platform organisms for cannabinoid biosynthesis
Bastian Zirpel et al.
JOURNAL OF BIOTECHNOLOGY (2017)
Identification of Iridoid Glucoside Transporters in Catharanthus roseus
Bo Larsen et al.
PLANT AND CELL PHYSIOLOGY (2017)
An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole
Richard M. E. Payne et al.
NATURE PLANTS (2017)
Plant ABC Transporters Enable Many Unique Aspects of a Terrestrial Plant's Lifestyle
Jae-Ung Hwang et al.
MOLECULAR PLANT (2016)
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Akira Nakagawa et al.
NATURE COMMUNICATIONS (2016)
Engineering of a Nepetalactol-Producing Platform Strain of Saccharomyces cerevisiae for the Production of Plant Seco-Iridoids
Alex Campbell et al.
ACS SYNTHETIC BIOLOGY (2016)
Cannabis sativa: The Plant of the Thousand and One Molecules
Christelle M. Andre et al.
FRONTIERS IN PLANT SCIENCE (2016)
The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation
Eric W. Bow et al.
PERSPECTIVES IN MEDICINAL CHEMISTRY (2016)
Characterization of a second secologanin synthase isoform producing both secologanin and secoxyloganin allows enhanced de novo assembly of a Catharanthus roseus transcriptome
Thomas Duge de Bernonville et al.
BMC GENOMICS (2015)
De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast
Isis J. Trenchard et al.
METABOLIC ENGINEERING (2015)
Iridoid Synthase Activity Is Common among the Plant Progesterone 5β-Reductase Family
Jennifer Munkert et al.
MOLECULAR PLANT (2015)
Stereochemical inversion of (S)-reticuline by a cytochrome P450 fusion in opium poppy
Scott C. Farrow et al.
NATURE CHEMICAL BIOLOGY (2015)
An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose
William C. DeLoache et al.
NATURE CHEMICAL BIOLOGY (2015)
Genome-guided investigation of plant natural product biosynthesis
Franziska Kellner et al.
PLANT JOURNAL (2015)
Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast
Yang Qua et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
De novo production of the plant-derived alkaloid strictosidine in yeast
Stephanie Brown et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Morphinan biosynthesis in opium poppy requires a P450-oxidoreductase fusion protein
Thilo Winzer et al.
SCIENCE (2015)
SYNTHETIC BIOLOGY Complete biosynthesis of opioids in yeast
Stephanie Galanie et al.
SCIENCE (2015)
A microbial biomanufacturing platform for natural and semisynthetic opioids
Kate Thodey et al.
NATURE CHEMICAL BIOLOGY (2014)
Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development
Chris J. Paddon et al.
NATURE REVIEWS MICROBIOLOGY (2014)
Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae
Elena Fossati et al.
NATURE COMMUNICATIONS (2014)
(R, S)-Tetrahydropapaveroline production by stepwise fermentation using engineered Escherichia coli
Akira Nakagawa et al.
SCIENTIFIC REPORTS (2014)
Improvement of Reticuline Productivity from Dopamine by Using Engineered Escherichia coli
Ju-Sung Kim et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2013)
High-level semi-synthetic production of the potent antimalarial artemisinin
C. J. Paddon et al.
NATURE (2013)
A Pair of Tabersonine 16-Hydroxylases Initiates the Synthesis of Vindoline in an Organ-Dependent Manner in Catharanthus roseus
Sebastien Besseau et al.
PLANT PHYSIOLOGY (2013)
ATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseus
Fang Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Redesign of a Dioxygenase in Morphine Biosynthesis
Weerawat Runguphan et al.
CHEMISTRY & BIOLOGY (2012)
Structure and Function of Δ1-Tetrahydrocannabinolic Acid (THCA) Synthase, the Enzyme Controlling the Psychoactivity of Cannabis sativa
Yoshinari Shoyama et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides
Steve J. Gagne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A bacterial platform for fermentative production of plant alkaloids
Akira Nakagawa et al.
NATURE COMMUNICATIONS (2011)
Integrating carbon-halogen bond formation into medicinal plant metabolism
Weerawat Runguphan et al.
NATURE (2010)
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy
Jillian M. Hagel et al.
NATURE CHEMICAL BIOLOGY (2010)
Norcoclaurine Synthase Is a Member of the Pathogenesis-Related 10/Bet v1 Protein Family
Eun-Jeong Lee et al.
PLANT CELL (2010)
Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway
Futoshi Taura et al.
FEBS LETTERS (2009)
CYP719B1 Is Salutaridine Synthase, the C-C Phenol-coupling Enzyme of Morphine Biosynthesis in Opium Poppy
Andreas Gesell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Halogenation strategies in natural product biosynthesis
Christopher S. Neumann et al.
CHEMISTRY & BIOLOGY (2008)
Alleviation of feedback inhibition in Saccharomyces cerevisiae aromatic amino acid biosynthesis: Quantification of metabolic impact
M. A. H. Luttik et al.
METABOLIC ENGINEERING (2008)
Microbial production of plant benzylisoquinoline alkaloids
Hiromichi Minami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa
Futoshi Taura et al.
FEBS LETTERS (2007)
L-tyrosine production by deregulated strains of Escherichia coli
Tina Lutke-Eversloh et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)
Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding
Susanne Frick et al.
METABOLIC ENGINEERING (2007)
Directed biosynthesis of alkaloid analogs in the medicinal plant Catharanthus roseus
Elizabeth McCoy et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis
Joerg Ziegler et al.
PLANT JOURNAL (2006)
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
DK Ro et al.
NATURE (2006)
The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed β-propeller fold in plant proteins
XY Ma et al.
PLANT CELL (2006)
Analysis of the reactions used for the preparation of drug candidate molecules
John S. Carey et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis
J Ziegler et al.
PLANTA (2005)
Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of the glandular trichomes
S Sirikantaramas et al.
PLANT AND CELL PHYSIOLOGY (2005)
Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy
PJ Facchini et al.
PHYTOCHEMISTRY (2003)
(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy
A Ounaroon et al.
PLANT JOURNAL (2003)
Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum
T Grothe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
