相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue
Boone M. Prentice et al.
DIABETOLOGIA (2019)
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer
Ming Chen et al.
NATURE GENETICS (2018)
An inhibitor of oxidative phosphorylation exploits cancer vulnerability
Jennifer R. Molina et al.
NATURE MEDICINE (2018)
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
Jasmine Chong et al.
NUCLEIC ACIDS RESEARCH (2018)
Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth
Ilenia Pacella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Fatty pancreas: A possible risk factor for pancreatic cancer in animals and humans
Mami Takahashi et al.
CANCER SCIENCE (2018)
Translating In Vitro T Cell Metabolic Findings to In Vivo Tumor Models of Nutrient Competition
Christopher Ecker et al.
CELL METABOLISM (2018)
Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid induced insulin resistance
Satoko Shinjo et al.
EXPERIMENTAL CELL RESEARCH (2017)
The why, when and how of lipid droplet diversity
Abdou Rachid Thiam et al.
JOURNAL OF CELL SCIENCE (2017)
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
Julienne L. Carstens et al.
NATURE COMMUNICATIONS (2017)
Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer
Jung-Eun Jang et al.
CELL REPORTS (2017)
Mevalonate Metabolism in Immuno-Oncology
Georg Gruenbacher et al.
FRONTIERS IN IMMUNOLOGY (2017)
Nutrient and Metabolic Sensing in T Cell Responses
Jun Wei et al.
FRONTIERS IN IMMUNOLOGY (2017)
Prognostic value of programmed cell death protein 1 expression on CD8+T lymphocytes in pancreatic cancer
Tao Shen et al.
SCIENTIFIC REPORTS (2017)
Immunotherapy in pancreatic cancer: Unleash its potential through novel combinations
Songchuan Guo et al.
WORLD JOURNAL OF CLINICAL ONCOLOGY (2017)
Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
Ying Zhang et al.
CANCER CELL (2017)
Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy
Rigel J. Kishton et al.
CELL METABOLISM (2017)
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
Alessia Angelin et al.
CELL METABOLISM (2017)
Foxp3 drives oxidative phosphorylation and protection from lipotoxicity
Duncan Howie et al.
JCI INSIGHT (2017)
Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response
Hyun-Eui Kim et al.
CELL (2016)
The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements
Claudio Procaccini et al.
IMMUNITY (2016)
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
Nicole E. Scharping et al.
IMMUNITY (2016)
Untargeted Metabolomics Strategies-Challenges and Emerging Directions
Alexandra C. Schrimpe-Rutledge et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2016)
Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
Wei Yang et al.
NATURE (2016)
Genomic analyses identify molecular subtypes of pancreatic cancer
Peter Bailey et al.
NATURE (2016)
The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells
Thomas Ploetz et al.
NUTRITION & METABOLISM (2016)
Prognostic impact of the tumor-infiltrating regulatory T-cell (Foxp3+)/activated cytotoxic T lymphocyte (granzyme B+) ratio on resected left-sided pancreatic cancer
Ho Kyoung Hwang et al.
ONCOLOGY LETTERS (2016)
Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma
Angela Diana et al.
ONCOTARGET (2016)
T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma
Ingunn M. Stromnes et al.
CANCER CELL (2015)
A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses
Marielle S. Koeberlin et al.
CELL (2015)
Nutrient Competition: A New Axis of Tumor Immunosuppression
Madhusudhanan Sukumar et al.
CELL (2015)
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
Ping-Chih Ho et al.
CELL (2015)
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih-Hao Chang et al.
CELL (2015)
Expanding Roles for Lipid Droplets
Michael A. Welte
CURRENT BIOLOGY (2015)
Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast
Jason D. Vevea et al.
DEVELOPMENTAL CELL (2015)
Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6Clow F4/80+ Extratumoral Macrophages
Gregory L. Beatty et al.
GASTROENTEROLOGY (2015)
T cell exclusion, immune privilege, and the tumor microenvironment
Johanna A. Joyce et al.
SCIENCE (2015)
T cell metabolic fitness in antitumor immunity
Peter J. Siska et al.
TRENDS IN IMMUNOLOGY (2015)
Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma
Rafael Winograd et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Mitochondria: hubs of cellular signaling, energetics and redox balance. A rich, vibrant, and diverse landscape of mitochondrial research
Miguel A. Aon et al.
FRONTIERS IN PHYSIOLOGY (2015)
The Molecular Signatures Database Hallmark Gene Set Collection
Arthur Liberzon et al.
CELL SYSTEMS (2015)
Development of non-alcoholic fatty liver disease scoring system among adult medical check-up patients: a large cross-sectional and prospective validation study
Cosmas Rinaldi A. Lesmana et al.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2015)
Molecular and cellular insights into T cell exhaustion
E. John Wherry et al.
NATURE REVIEWS IMMUNOLOGY (2015)
The lipid droplet-a well-connected organelle
Qiang Gao et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2015)
Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia
Florencia McAllister et al.
CANCER CELL (2014)
Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling
Irfan J. Lodhi et al.
CELL METABOLISM (2014)
Lipotoxicity in the Pancreatic Beta Cell: Not Just Survival and Function, but Proliferation as Well?
Rohit B. Sharma et al.
CURRENT DIABETES REPORTS (2014)
Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development
David O'Sullivan et al.
IMMUNITY (2014)
Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique
Angela Messina et al.
MOLECULAR BIOSYSTEMS (2014)
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
Luciana Berod et al.
NATURE MEDICINE (2014)
Pancreatic Fatty Degeneration and Fibrosis as Predisposing Factors for the Development of Pancreatic Ductal Adenocarcinoma
Yasuhiko Tomita et al.
PANCREAS (2014)
Molecular assessment of surgical-resection margins of gastric cancer by mass-spectrometric imaging
Livia S. Eberlin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Imaging mass spectrometry to discriminate breast from pancreatic cancer metastasis in formalin- fixed paraffin- embedded tissues
Rita Casadonte et al.
PROTEOMICS (2014)
CD4+ T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice
Yaqing Zhang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Mitochondrial and cellular mechanisms for managing lipid excess
Miguel A. Aon et al.
FRONTIERS IN PHYSIOLOGY (2014)
Association of Pancreatic Fatty Infiltration With Pancreatic Ductal Adenocarcinoma
Mika Hori et al.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2014)
Chimeric antigen receptor T cells are vulnerable to immunosuppressive mechanisms present within the tumor microenvironment
Gregory L. Beatty et al.
ONCOIMMUNOLOGY (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
Y. Ino et al.
BRITISH JOURNAL OF CANCER (2013)
Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma
Abasi Ene-Obong et al.
GASTROENTEROLOGY (2013)
Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling
Laura A. Sena et al.
IMMUNITY (2013)
Immune infiltrates as predictive markers of survival in pancreatic cancer patients
Maria Pia Protti et al.
FRONTIERS IN PHYSIOLOGY (2013)
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
Gerritje J. W. van der Windt et al.
IMMUNITY (2012)
Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer
Julie R. Brahmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer
Barbara M. Gruener et al.
PLOS ONE (2012)
Tissue-Specific Strategies of the Very-Long Chain Acyl-CoA Dehydrogenase-Deficient (VLCAD-/-) Mouse to Compensate a Defective Fatty Acid β-Oxidation
Sara Tucci et al.
PLOS ONE (2012)
Is fat so bad? Modulation of endoplasmic reticulum stress by lipid droplet formation
Ivan Hapala et al.
BIOLOGY OF THE CELL (2011)
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
Lucia De Monte et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Cancer immunotherapy comes of age
Ira Mellman et al.
NATURE (2011)
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
Suneng Fu et al.
NATURE (2011)
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
Kristin M. Nieman et al.
NATURE MEDICINE (2011)
The clinical significance of pancreatic steatosis
Mark M. Smits et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)
Lipid Rafts As a Membrane-Organizing Principle
Daniel Lingwood et al.
SCIENCE (2010)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue
Dale S. Cornett et al.
ANALYTICAL CHEMISTRY (2008)
Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
Candace M. Cham et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Glucose uptake is limiting in T cell activation and requires CD28-mediated akt-dependent and independent pathways
Sarah R. Jacobs et al.
JOURNAL OF IMMUNOLOGY (2008)
mMass data miner: an open source alternative for mass spectrometric data analysis
Martin Strohalm et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2008)
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
E. John Wherry et al.
IMMUNITY (2007)
Lipid rafts in T cell signalling and disease
Elizabeth C. Jury et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2007)
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
Carolyn E. Clark et al.
CANCER RESEARCH (2007)
Sublimation as a method of matrix application for mass spectrometric imaging
Joseph A. Hankin et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2007)
LIPID MAPS online tools for lipid research
Eoin Fahy et al.
NUCLEIC ACIDS RESEARCH (2007)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
Glucose availability regulates IFN-γ production and p70S6 kinase activation in CD8+ effector T cells
CM Cham et al.
JOURNAL OF IMMUNOLOGY (2005)
CD8(+) tumor-infiltrating lymphocytes together with CD4(+) tumor-infiltrating lymphocytes and dendritic cells improve the prognosis of patients with pancreatic adenocarcinoma
A Fukunaga et al.
PANCREAS (2004)
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani et al.
CANCER CELL (2003)
Molecular and phenotypic heterogeneity in mitochondrial trifunctional protein deficiency due to β-subunit mutations
U Spiekerkoetter et al.
HUMAN MUTATION (2003)
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Palmitic and stearic fatty acids induce caspase-dependent and -independent cell death in nerve growth factor differentiated PC12 cells
JE Ulloth et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
UK Liyanage et al.
JOURNAL OF IMMUNOLOGY (2002)
MUC1-specific CTLs are non-functional within a pancreatic tumor microenvironment
P Mukherjee et al.
GLYCOCONJUGATE JOURNAL (2001)
The role of lipid rafts in T cell antigen receptor (TCR) signalling
PW Janes et al.
SEMINARS IN IMMUNOLOGY (2000)