期刊
JOURNAL OF COLLOID AND INTERFACE SCIENCE
卷 581, 期 -, 页码 465-474出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2020.07.076
关键词
Antimony oxides; Nanomaterial; Electrochemical sensor; In situ; Nitric oxide
资金
- Southwest University
- Suzhou University of Science and Technology
- Fundamental Research Funds for the Central Universities [XDJK2019B002]
The Sb2O4 nanoflowers/rGO nanocomposite sensor shows excellent detection performance for NO oxidation, with real-time detection of NO release from living cells showing significant differences between normal and tumor cells, indicating great potential for biomedical applications.
Nitric oxide (NO) is an important bio-regulatory and signaling molecule associated with various physiological and pathophysiological pathways, but its sensitive real-time detection is still very challenging due to the low concentration, large diffusivity and fast decay in biological samples. Here an antimony tetroxide (Sb2O4) nanoflowers/reduced graphene oxide (rGO) nanocomposite is synthesized via a facile and eco-friendly solvothermal method to merit-combine highly electroactive Sb2O4 nanoflowers with large surficial rGO component for a strong synergistic effect on oxidation of NO. Results demonstrate that the Sb2O4/rGO-based sensor has a low detection limit, high sensitivity, excellent selectivity and fast response for NO detection. The real-time detected NO released from living cells showed significant difference between normal and tumor cells. The Sb2O4 nanoflowers/rGO nanocomposite sensor holds a great promise for important applications in biomedical research fields and clinical diagnosis. (C) 2020 Published by Elsevier Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据