Mechanics Strategies for Implantation of Flexible Neural Probes

Flexible polymer-based neural probes are promising tools to interfaces with brain tissue since the low stiffness and thin geometry of these probes make them compliant to soft tissue in a manner that allows for reducing the inflammation responses. However, the same properties make flexible probes susceptible to bending and buckling during insertion, which make the implantation impossible. This paper provides a brief review of recent advances in mechanics strategies to assist the insertion of flexible probes. The basic concept of each strategy is summarized with advantages and disadvantages briefly discussed. These results provide a guide for reliable implantations of flexible neural probes for chronic brain electrophysiological recording and clinical treatment of neurological disorders.

Automated summary

This paper reviews recent advances in mechanics strategies to facilitate the insertion of flexible neural probes, summarizing the basic concepts of each strategy and discussing their advantages and disadvantages briefly. The results provide guidance for reliable implantation of flexible neural probes for chronic brain electrophysiological recording and the clinical treatment of neurological disorders.