4.5 Article

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent A beta PP-beta Cleavage Decreasing Amyloid-beta Production and Accumulation in Alzheimer's Disease Models

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Neurosciences

Modulation of gamma- and beta-Secretases as Early Prevention Against Alzheimer's Disease

Iryna Voytyuk et al.

BIOLOGICAL PSYCHIATRY (2018)

Article Immunology

Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice

Angie C. A. Chiang et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Article Medicine, General & Internal

Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer's Disease

Michael F. Egan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Chemistry, Multidisciplinary

Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment

Judite R. M. Coimbra et al.

FRONTIERS IN CHEMISTRY (2018)

Article Medicine, Research & Experimental

The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease

Ulf Neumann et al.

EMBO MOLECULAR MEDICINE (2018)

Article Cell Biology

Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice

Ming-Hsuan Ou-Yang et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Review Pharmacology & Pharmacy

Beta-secretase inhibitors in phase I and phase II clinical trials for Alzheimer's disease

Charbel E-H. Moussa

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2017)

Article Multidisciplinary Sciences

BACE inhibition-dependent repair of Alzheimer's pathophysiology

Aylin D. Keskin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Pharmacology & Pharmacy

Cell-Penetrating Peptides: From Basic Research to Clinics

Giulia Guidotti et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2017)

Review Neurosciences

Role of BACE1 in Alzheimer's synaptic function

Brati Das et al.

TRANSLATIONAL NEURODEGENERATION (2017)

Article Clinical Neurology

Decreased Plasma β-Amyloid in the Alzheimer's Disease APP A673T Variant Carriers

Henna Martiskainen et al.

ANNALS OF NEUROLOGY (2017)

Review Medicine, Research & Experimental

The amyloid hypothesis of Alzheimer's disease at 25years

Dennis J. Selkoe et al.

EMBO MOLECULAR MEDICINE (2016)

Article Biochemistry & Molecular Biology

Functions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System

Kathryn M. Munro et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2016)

Review Veterinary Sciences

Euthanasia using gaseous agents in laboratory rodents

A. M. Valentim et al.

LABORATORY ANIMALS (2016)

Article Biochemistry & Molecular Biology

PEP-FOLD3: faster denovo structure prediction for linear peptides in solution and in complex

Alexis Lamiable et al.

NUCLEIC ACIDS RESEARCH (2016)

Editorial Material Hospitality, Leisure, Sport & Tourism

BACE1 inhibition as a therapeutic strategy for Alzheimer's disease

Robert Vassar

Journal of Sport and Health Science (2016)

Review Neurosciences

Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs

Riqiang Yan

TRANSLATIONAL NEURODEGENERATION (2016)

Article Medicine, General & Internal

Alzheimer's disease

Colin L. Masters et al.

NATURE REVIEWS DISEASE PRIMERS (2015)

Article Multidisciplinary Sciences

Cell-Penetrating Peptides Selectively Cross the Blood-Brain Barrier In Vivo

Sofie Stalmans et al.

PLOS ONE (2015)

Review Chemistry, Multidisciplinary

BACE1 (beta-secretase) inhibitors for the treatment of Alzheimer's disease

Arun K. Ghosh et al.

CHEMICAL SOCIETY REVIEWS (2014)

Article Biochemistry & Molecular Biology

Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein

Janice A. Maloney et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Review Clinical Neurology

Targeting the β secretase BACE1 for Alzheimer's disease therapy

Riqiang Yan et al.

LANCET NEUROLOGY (2014)

Review Clinical Neurology

BACE1 inhibitor drugs in clinical trials for Alzheimer's disease

Robert Vassar

ALZHEIMERS RESEARCH & THERAPY (2014)

Article Multidisciplinary Sciences

A mutation in APP protects against Alzheimer's disease and age-related cognitive decline

Thorlakur Jonsson et al.

NATURE (2012)

Article Biochemical Research Methods

Cell-Penetrating Peptides, PepFects, Show No Evidence of Toxicity and Immunogenicity In Vitro and In Vivo

Julia Suhorutsenko et al.

BIOCONJUGATE CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

β-Secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice

Wan-Pin Chang et al.

FASEB JOURNAL (2011)

Article Biochemistry & Molecular Biology

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

Weihong Tu et al.

Article Biotechnology & Applied Microbiology

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

Dries Vercauteren et al.

MOLECULAR THERAPY (2010)

Review Pharmacology & Pharmacy

In vivo biodistribution and efficacy of peptide mediated delivery

Peter Jarver et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Article Oncology

Effect of RasGAP N2 Fragment-Derived Peptide on Tumor Growth in Mice

David Michod et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)

Article Neurosciences

Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus

Daniela Puzzo et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Biochemistry & Molecular Biology

Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP transgenic mice

Lisa McConlogue et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide

EL Snyder et al.

PLOS BIOLOGY (2004)

Article Biochemistry & Molecular Biology

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

T Borsello et al.

NATURE MEDICINE (2003)

Article Chemistry, Multidisciplinary

HADDOCK: A protein-protein docking approach based on biochemical or biophysical information

C Dominguez et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)