期刊
JOURNAL OF ALZHEIMERS DISEASE
卷 76, 期 2, 页码 467-473出版社
IOS PRESS
DOI: 10.3233/JAD-191195
关键词
Agitation; dementia; neuropsychiatric symptoms; nursing homes
资金
- UCLH NIHR BRC
- National Institute of Health Research [NIHR/ESRC ES/L001780/1]
- UK Economic and Social Research Council
- ESRC [ES/L001780/1] Funding Source: UKRI
Care home residents with dementia often have accompanying agitation. We investigated agitation's course at 5 time-points in 1,424 people with dementia over 16 months in 86 English care homes. We categorized baseline agitation symptoms on the Cohen-Mansfield Agitation Inventory (CMAI) into none (CMAI = 29; 15%), subclinical (CMAI = 30-45; 45%), or clinically-significant (CMAI 45; 40%). 88% of those with no agitation at baseline remained free of clinically-significant agitation at all follow-ups. Seventy percent of those exhibiting clinically-significant agitation at baseline had clinically-significant agitation at some follow-ups. Over a 16-month observation period, this study finds many care home residents with dementia never develop clinically significant agitation and interventions should be for treatment not prevention.
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