Gold nanorods-coated reduced graphene oxide as a modified electrode for the electrochemical sensory detection of NADH

We have reported a simple chemical preparation method of gold nanorods (AuNR) incorporated reduced graphene oxide (rGO) nanocomposite. Thus, synthesized AuNR decorated rGO (AuNR@rGO) nanocomposite has directly coated on glassy carbon electrode (GCE) for the highly sensitive and selective electrochemical sensing of Dihydronicotinamide adenine dinucleotide (NADH). The electrocatalytic activity of AuNR@rGO/GCE-modified electrode towards the oxidation of NADH has elaborately discussed. From the analysis of results, the amperometric current is increased linearly while increasing the NADH concentration in the range of 1-31 mu M and the small limit of detection (LoD) has estimated as 0.22 mu M (S/N = 3). Furthermore, the interferent study of the AuNR@rGO/GCE-modified electrode confirms for the sensitivity and unique detection ability of the electrode when other competitive biomolecules like glucose, uric acid, ascorbic acid, and dopamine are present. (C) 2020 Elsevier B.V. All rights reserved.