期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 21, 期 15, 页码 -出版社
MDPI
DOI: 10.3390/ijms21155307
关键词
plant defensin; structure; dynamics; gamma-core; NMR; x-ray; oligomer; dimer; antifungal; antibacterial
资金
- U.S. Civilian Research & Development Foundation (CRDF Global) [FSA-19-65490-0, FSA-19-65490-1]
- Ministry of Education and Science of Ukraine [0120U103353]
Plant defensins form a family of proteins with a broad spectrum of protective activities against fungi, bacteria, and insects. Furthermore, some plant defensins have revealed anticancer activity. In general, plant defensins are non-toxic to plant and mammalian cells, and interest in using them for biotechnological and medicinal purposes is growing. Recent studies provided significant insights into the mechanisms of action of plant defensins. In this review, we focus on structural and dynamics aspects and discuss structure-dynamics-function relations of plant defensins.
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