相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Nucleotide-binding oligomerization domain protein 2 deficiency enhances CHOP expression and plaque necrosis in advanced atherosclerotic lesions
Min-Young Kwon et al.
FEBS JOURNAL (2020)
NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS
Xiao Man Wu et al.
JOURNAL OF IMMUNOLOGY (2020)
Synthetic mycobacterial molecular patterns partially complete Freund's adjuvant
Jean-Yves Dube et al.
SCIENTIFIC REPORTS (2020)
Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress
Raphael Molinaro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The role of autophagy in maintaining intestinal mucosal barrier
Yanping Wu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
The association of nucleotide-binding oligomerization domain 2 gene polymorphisms with the risk of asthma in the Chinese Han population
Xulong Cai et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2019)
Frontline Science: Abnormalities in the gut mucosa of non-obese diabetic mice precede the onset of type 1 diabetes
Mariana Camila Goncalves Miranda et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2019)
Role of peptide transporter 2 and MAPK signaling pathways in the innate immune response induced by bacterial peptides in alveolar epithelial cells
Mikihisa Takano et al.
LIFE SCIENCES (2019)
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling
Mena Abdel-Nour et al.
SCIENCE (2019)
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing
Yan Lu et al.
SCIENCE (2019)
Mechanisms of Disease: Inflammatory Bowel Diseases
Guilherme Piovezani Ramos et al.
MAYO CLINIC PROCEEDINGS (2019)
A Novel NOD2-associated Mutation and Variant Blau Syndrome: Phenotype and Molecular Analysis
Nazanin Ebrahimiadib et al.
OCULAR IMMUNOLOGY AND INFLAMMATION (2018)
A Novel Mutation in Helical Domain 2 of NOD2 in Sporadic Blau Syndrome
Lubhani Jain et al.
OCULAR IMMUNOLOGY AND INFLAMMATION (2018)
NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells
Le Son Tran et al.
CELLULAR MICROBIOLOGY (2018)
Novel NOD2 Mutation in Early-Onset Inflammatory Bowel Phenotype
Martina Girardelli et al.
INFLAMMATORY BOWEL DISEASES (2018)
Using genes to triangulate the pathophysiology of granulomatous autoinflammatory disease: NOD2, PLCG2 and LACC1
Ann Marie Szymanski et al.
INTERNATIONAL IMMUNOLOGY (2018)
NOD1 and NOD2: Molecular targets in prevention and treatment of infectious diseases
Mikhail V. Pashenkov et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages
Yongjun Hu et al.
JOURNAL OF IMMUNOLOGY (2018)
Local Stimulation of Liver Sinusoidal Endothelial Cells with a NOD1 Agonist Activates T Cells and Suppresses Hepatitis B Virus Replication in Mice
Shunmei Huang et al.
JOURNAL OF IMMUNOLOGY (2018)
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis
Mark S. Gresnigt et al.
NATURE COMMUNICATIONS (2018)
Outer Membrane Vesicles From Probiotic and Commensal Escherichia coli Activate NOD1-Mediated Immune Responses in Intestinal Epithelial Cells
Maria-Alexandra Canas et al.
FRONTIERS IN MICROBIOLOGY (2018)
Frontline Science: RIP2 promotes house dust mite-induced allergic airway inflammation
Madelyn H. Miller et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2018)
RIP2 filament formation is required for NOD2 dependent NF-κB signalling
Erika Pellegrini et al.
NATURE COMMUNICATIONS (2018)
Genetic deletion of the bacterial sensor NOD2 improves murine Crohn's disease-like ileitis independent of functional dysbiosis
D. Corridoni et al.
MUCOSAL IMMUNOLOGY (2017)
Molecular Recognition of Muramyl Dipeptide Occurs in the Leucine-rich Repeat Domain of Nod2
Mackenzie L. Lauro et al.
ACS INFECTIOUS DISEASES (2017)
Environmental Risk Factors for Type 1 Diabetes Mellitus Development
Boljat Antonela et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2017)
A novel nucleotide oligomerisation domain 2 mutation in a family with Blau syndrome: Phenotype and function
Lawrence T. C. Ong et al.
INNATE IMMUNITY (2017)
Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells
Haifang Wang et al.
JOURNAL OF IMMUNOLOGY (2017)
Gut microbiota and IBD: causation or correlation?
Josephine Ni et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions
William H. Conrad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
NOD1 and NOD2: Beyond Peptidoglycan Sensing
A. Marijke Keestra-Gounder et al.
TRENDS IN IMMUNOLOGY (2017)
NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways
S. M. Nashir Udden et al.
CELL REPORTS (2017)
Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance
Kenny L. Chan et al.
CELL REPORTS (2017)
M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1
Murugesan V. S. Rajaram et al.
CELL REPORTS (2017)
The Absence of NOD1 Enhances Killing of &ITAspergillus fumigatus&IT Through Modulation of Dectin-1 Expression
Mark S. Gresnigt et al.
FRONTIERS IN IMMUNOLOGY (2017)
Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction
Ivan Rodriguez-Nunez et al.
SCIENTIFIC REPORTS (2017)
Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4
Joseph F. Cavallari et al.
CELL METABOLISM (2017)
NOD2 promotes cell proliferation and inflammatory response by mediating expression of TSLP in human airway smooth muscle cells
Gaoshun Ni et al.
CELLULAR IMMUNOLOGY (2017)
The role of nucleotide-binding oligomerization domain 1 during cytokine production by macrophages in response to Mycobacterium tuberculosis infection
Jun-Young Lee et al.
IMMUNOBIOLOGY (2016)
Muramyl peptides activate innate immunity conjointly via YB1 and NOD2
Alexander G. Laman et al.
INNATE IMMUNITY (2016)
Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset
Frederico R. C. Costa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Nod1 Limits Colitis-Associated Tumorigenesis by Regulating IFN-γ Production
Yu Zhan et al.
JOURNAL OF IMMUNOLOGY (2016)
NOD1 Participates in the Innate Immune Response Triggered by Hepatitis C Virus Polymerase
Serena Vegna et al.
JOURNAL OF VIROLOGY (2016)
Environmental risk factors for type 1 diabetes
Marian Rewers et al.
LANCET (2016)
NOD1/NOD2 signaling links ER stress with inflammation
A. Marijke Keestra-Gounder et al.
NATURE (2016)
Regulating Rho GTPases and their regulators
Richard G. Hodge et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo
Yi-Hsin Fan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease
Hiutung Chu et al.
SCIENCE (2016)
Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
Johnathan Canton et al.
NATURE COMMUNICATIONS (2016)
Crystal structure of NOD2 and its implications in human disease
Sakiko Maekawa et al.
NATURE COMMUNICATIONS (2016)
Is there any association between Sarcoidosis and infectious agents?: a systematic review and meta-analysis
Tiago Esteves et al.
BMC PULMONARY MEDICINE (2016)
CYLD Limits Lys63-and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling
Matous Hrdinka et al.
CELL REPORTS (2016)
Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-β-Dependent Pathway
Arun Kapoor et al.
SCIENTIFIC REPORTS (2016)
Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance
Emmanuel Denou et al.
EMBO MOLECULAR MEDICINE (2015)
Peptidoglycan perception-Sensing bacteria by their common envelope structure
Ute Bertsche et al.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2015)
Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation
Prashant K. Nighot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin
Yolanda Corbett et al.
MICROBES AND INFECTION (2015)
Commensal bacteria direct selective cargo sorting to promote symbiosis
Qin Zhang et al.
NATURE IMMUNOLOGY (2015)
Increased NOD1, but not NOD2, activity in subcutaneous adipose tissue from patients with metabolic syndrome
Yi-Jun Zhou et al.
OBESITY (2015)
Mechanisms Linking Inflammation to Insulin Resistance
Li Chen et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2015)
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
Peter Draber et al.
CELL REPORTS (2015)
Optic nerve and retinal features in uveitis associated with juvenile systemic granulomatous disease (Blau syndrome)
Ester Carreno et al.
ACTA OPHTHALMOLOGICA (2015)
Blau Syndrome-Associated Nod2 Mutation Alters Expression of Full-Length NOD2 and Limits Responses to Muramyl Dipeptide in Knock-in Mice
Jae Dugan et al.
JOURNAL OF IMMUNOLOGY (2015)
CCL17 Production by Dendritic Cells Is Required for NOD1-mediated Exacerbation of Allergic Asthma
Saliha Ait Yahia et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling
Aaron T. Irving et al.
CELL HOST & MICROBE (2014)
The Cytosolic Bacterial Peptidoglycan Sensor Nod2 Affords Stem Cell Protection and Links Microbes to Gut Epithelial Regeneration
Giulia Nigro et al.
CELL HOST & MICROBE (2014)
Aspergillus fumigatus triggers innate immune response via NOD1 signaling in human corneal epithelial cells
Yuting Zhang et al.
EXPERIMENTAL EYE RESEARCH (2014)
Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators
Rhiannon Parkhouse et al.
FEBS LETTERS (2014)
Genetic Variants Synthesize to Produce Paneth Cell Phenotypes That Define Subtypes of Crohn's Disease
Kelli L. VanDussen et al.
GASTROENTEROLOGY (2014)
NOD2 and CCDC122-LACC1 genes are associated with leprosy susceptibility in Brazilians
Carolinne Sales-Marques et al.
HUMAN GENETICS (2014)
Bacterial Sensor Nod2 Prevents Inflammation of the Small Intestine by Restricting the Expansion of the Commensal Bacteroides vulgatus
Deepshika Ramanan et al.
IMMUNITY (2014)
Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils
Yu-Jin Jeong et al.
IMMUNOLOGY (2014)
Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles Are Internalized in Human Host Cells and Trigger NOD1- and NOD2-Dependent NF-κB Activation
Bernard Thay et al.
INFECTION AND IMMUNITY (2014)
Peptidoglycan Recognition Protein 3 and Nod2 Synergistically Protect Mice from Dextran Sodium Sulfate-Induced Colitis
Xuefang Jing et al.
JOURNAL OF IMMUNOLOGY (2014)
Nucleotide Oligomerization and Binding Domain 2-Dependent Dendritic Cell Activation Is Necessary for Innate Immunity and Optimal CD8+ T Cell Responses to Influenza A Virus Infection
Christopher Lupfer et al.
JOURNAL OF VIROLOGY (2014)
Endosomes are specialized platforms for bacterial sensing and NOD2 signalling
Norihiro Nakamura et al.
NATURE (2014)
Activation of Nucleotide Oligomerization Domain 2 (NOD2) by Human Cytomegalovirus Initiates Innate Immune Responses and Restricts Virus Replication
Arun Kapoor et al.
PLOS ONE (2014)
Nucleotide-Oligomerization-Domain-2 Affects Commensal Gut Microbiota Composition and Intracerebral Immunopathology in Acute Toxoplasma gondii Induced Murine Ileitis
Markus M. Heimesaat et al.
PLOS ONE (2014)
Nucleotide-oligomerizing domain-1 (NOD1) receptor activation induces pro-inflammatory responses and autophagy in human alveolar macrophages
Esmeralda Juarez et al.
BMC PULMONARY MEDICINE (2014)
Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation
Jeanette Wagener et al.
PLOS PATHOGENS (2014)
Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications
Dmitry A. Chistiakov et al.
BIOMED RESEARCH INTERNATIONAL (2014)
The intermediate filament protein, vimentin, is a regulator of NOD2 activity
Craig Stevens et al.
GUT (2013)
The Intracellular Sensor NOD2 Induces MicroRNA-29 Expression in Human Dendritic Cells to Limit IL-23 Release
Oliver Brain et al.
IMMUNITY (2013)
Vibrio cholerae O395 Outer Membrane Vesicles Modulate Intestinal Epithelial Cells in a NOD1 Protein-dependent Manner and Induce Dendritic Cell-mediated Th2/Th17 Cell Responses
Debashree Chatterjee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
Berthe Katrine Fiil et al.
MOLECULAR CELL (2013)
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1
A. Marijke Keestra et al.
NATURE (2013)
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Shuo Yang et al.
NATURE IMMUNOLOGY (2013)
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
Christopher Lupfer et al.
NATURE IMMUNOLOGY (2013)
Blau Syndrome-Associated Uveitis and the NOD2 Gene
Parvathy Pillai et al.
SEMINARS IN OPHTHALMOLOGY (2013)
The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity
Amit P. Bhavsar et al.
PLOS PATHOGENS (2013)
Comparative genomic and sequence analysis provides insign into the molecular functionality of NOD1 and NOD2
Joseph P. Boyle et al.
FRONTIERS IN IMMUNOLOGY (2013)
Compromised autophagy by MIR30B benefits the intracellular survival of Helicobacter pylori
Bin Tang et al.
AUTOPHAGY (2012)
A novel single nucleotide polymorphism within the NOD2 gene is associated with pulmonary tuberculosis in the Chinese Han, Uygur and Kazak populations
Mengyuan Zhao et al.
BMC INFECTIOUS DISEASES (2012)
被撤回的出版物: NOD2 Signaling Contributes to Host Defense in the Lungs against Escherichia coli Infection (Retracted article. See vol. 83, pg. 2199, 2015)
Balamayooran Theivanthiran et al.
INFECTION AND IMMUNITY (2012)
Commensal and probiotic bacteria influence intestinal barrier function and susceptibility to colitis in Nod1-/-;Nod2-/- Mice
Jane M. M. Natividad et al.
INFLAMMATORY BOWEL DISEASES (2012)
Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation
Birte Zurek et al.
INNATE IMMUNITY (2012)
Morphologic and immunohistochemical characterization of granulomas in the nucleotide oligomerization domain 2-related disorders Blau syndrome and Crohn disease
Carl E. I. Janssen et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP
Jinyao Mo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Hereditary Autoinflammatory Syndromes: A Brazilian Multicenter Study
Adriana A. Jesus et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2012)
Crohn's Disease Susceptibility Genes are Associated With Leprosy in the Vietnamese Population
Audrey V. Grant et al.
JOURNAL OF INFECTIOUS DISEASES (2012)
Blau Arteritis Resembling Takayasu Disease with a Novel NOD2 Mutation
Raju P. Khubchandani et al.
JOURNAL OF RHEUMATOLOGY (2012)
The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment
Catherine Leimkuhler Grimes et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Rune Busk Damgaard et al.
MOLECULAR CELL (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Muramyl Dipeptide Induces NOD2-Dependent Ly6Chigh Monocyte Recruitment to the Lungs and Protects Against Influenza Virus Infection
Francois Coulombe et al.
PLOS ONE (2012)
RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition
Simone Lipinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA
Kathryn A. Knoop et al.
FRONTIERS IN IMMUNOLOGY (2012)
Dysregulation of p38 and MKP-1 in Response to NOD1/TLR4 Stimulation in Sarcoid Bronchoalveolar Cells
Ruchi Rastogi et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Nucleotide-Binding Oligomerization Domain Protein 2 Deficiency Enhances Neointimal Formation in Response to Vascular Injury
Min-Young Kwon et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Viral Infection Augments Nod1/2 Signaling to Potentiate Lethality Associated with Secondary Bacterial Infections
Yun-Gi Kim et al.
CELL HOST & MICROBE (2011)
NOD1 Activators Link Innate Immunity to Insulin Resistance
Jonathan D. Schertzer et al.
DIABETES (2011)
Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii
Braulia C. Caetano et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
The Solute Carrier Family 15A4 Regulates TLR9 and NOD1 Functions in the Innate Immune System and Promotes Colitis in Mice
Shigemi Sasawatari et al.
GASTROENTEROLOGY (2011)
Nod2 is essential for temporal development of intestinal microbial communities
Ateequr Rehman et al.
GUT (2011)
The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
Yun-Gi Kim et al.
IMMUNITY (2011)
Signaling via the RIP2 Adaptor Protein in Central Nervous System-Infiltrating Dendritic Cells Promotes Inflammation and Autoimmunity
Patrick J. Shaw et al.
IMMUNITY (2011)
Nucleotide-binding and oligomerization domain-like receptors and retinoic acid inducible gene-like receptors in human tonsillar T lymphocytes
Terese Petterson et al.
IMMUNOLOGY (2011)
NOD-Like Receptor Activation by Outer Membrane Vesicles from Vibrio cholerae Non-O1 Non-O139 Strains Is Modulated by the Quorum-Sensing Regulator HapR
H. Bielig et al.
INFECTION AND IMMUNITY (2011)
Disease Phenotype and Genotype Are Associated with Shifts in Intestinal-associated Microbiota in Inflammatory Bowel Diseases
Daniel N. Frank et al.
INFLAMMATORY BOWEL DISEASES (2011)
Immunophenotyping in peripheral blood mononuclear cells, aqueous humour and vitreous in a Blau syndrome patient caused by a novel NOD2 mutation
M. C. Jimenez-Martinez et al.
INTERNATIONAL JOURNAL OF IMMUNOGENETICS (2011)
L-Ala-γ-D-Glu-meso-diaminopimelic Acid (DAP) Interacts Directly with Leucine-rich Region Domain of Nucleotide-binding Oligomerization Domain 1, Increasing Phosphorylation Activity of Receptor-interacting Serine/Threonine-protein Kinase 2 and Its Interaction with Nucleotide-binding Oligomerization Domain 1
Hamed Laroui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice
Kimberly M. Davis et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Cutting Edge: Crohn's Disease-Associated Nod2 Mutation Limits Production of Proinflammatory Cytokines To Protect the Host from Enterococcus faecalis-Induced Lethality
Yun-Gi Kim et al.
JOURNAL OF IMMUNOLOGY (2011)
Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen
Mizuho Hasegawa et al.
JOURNAL OF IMMUNOLOGY (2011)
Effects of NOD-like receptors in human B lymphocytes and crosstalk between NOD1/NOD2 and Toll-like receptors
Terese Petterson et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2011)
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
Manuel A. Rivas et al.
NATURE GENETICS (2011)
Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation
Joao G. Magalhaes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Distinguishing between the innate immune response due to ocular inflammation and infection in a child with juvenile systemic granulomatous disease treated with anti-TNF-α monoclonal antibodies
Srilakshmi M. Sharma et al.
RHEUMATOLOGY (2011)
A Salmonella Virulence Factor Activates the NOD1/NOD2 Signaling Pathway
A. Marijke Keestra et al.
MBIO (2011)
Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion
Takahiro Shimada et al.
CELL HOST & MICROBE (2010)
The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides
Alexandra Grubman et al.
CELLULAR MICROBIOLOGY (2010)
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells
Maria Kaparakis et al.
CELLULAR MICROBIOLOGY (2010)
ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis
Craig R. Homer et al.
GASTROENTEROLOGY (2010)
Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model
Kaoru Geddes et al.
INFECTION AND IMMUNITY (2010)
NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway
Tomohiro Watanabe et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Nucleotide Oligomerization Binding Domain-Like Receptor Signaling Enhances Dendritic Cell-Mediated Cross-Priming In Vivo
Jumpei Asano et al.
JOURNAL OF IMMUNOLOGY (2010)
Recognition of Borrelia burgdorferi by NOD2 Is Central for the Induction of an Inflammatory Reaction
Marije Oosting et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
Leonardo H. Travassos et al.
NATURE IMMUNOLOGY (2010)
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
Rachel Cooney et al.
NATURE MEDICINE (2010)
Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
Amlan Biswas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A case of early-onset sarcoidosis with a six-base deletion in the NOD2 gene
Hidemasa Sakai et al.
RHEUMATOLOGY (2010)
Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: A meta-analysis
Wei-Guo Lu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2010)
Disruption of Nod-like Receptors Alters Inflammatory Response to Infection but Does Not Confer Protection in Experimental Cerebral Malaria
Constance A. M. Finney et al.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2009)
NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease
Grace Chen et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2009)
Incomplete Penetrance of the NOD2 E383K Substitution Among Members of a Pediatric Granulomatous Arthritis Pedigree
Frank T. Saulsbury et al.
ARTHRITIS AND RHEUMATISM (2009)
NOD2-Associated Pediatric Granulomatous Arthritis, an Expanding Phenotype Study of an International Registry and a National Cohort in Spain
Carlos D. Rose et al.
ARTHRITIS AND RHEUMATISM (2009)
Role of the NOD2 Genotype in the Clinical Phenotype of Blau Syndrome and Early-Onset Sarcoidosis
Ikuo Okafuji et al.
ARTHRITIS AND RHEUMATISM (2009)
Frequency of single nucleotide polymorphisms in NOD1 gene of ulcerative colitis patients: a case-control study in the Indian population
Ravi Verma et al.
BMC MEDICAL GENETICS (2009)
Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2
Mathieu J. M. Bertrand et al.
IMMUNITY (2009)
Critical Role of NOD2 in Regulating the Immune Response to Staphylococcus aureus
Hitesh S. Deshmukh et al.
INFECTION AND IMMUNITY (2009)
Nonhematopoietic Cells Control the Outcome of Infection with Listeria monocytogenes in a Nucleotide Oligomerization Domain 1-Dependent Manner
Ahmed Mosa et al.
INFECTION AND IMMUNITY (2009)
pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling
Jooeun Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation
Noemi Marina-Garcia et al.
JOURNAL OF IMMUNOLOGY (2009)
Helicobacter pylori Induces MAPK Phosphorylation and AP-1 Activation via a NOD1-Dependent Mechanism
Cody C. Allison et al.
JOURNAL OF IMMUNOLOGY (2009)
Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1
Christian Enevold et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Activation of innate immune antiviral responses by Nod2
Ahmed Sabbah et al.
NATURE IMMUNOLOGY (2009)
T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii
Michael H. Shaw et al.
NATURE IMMUNOLOGY (2009)
Genomewide Association Study of Leprosy
Fu-Ren Zhang et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Nod2 is required for the regulation of commensal microbiota in the intestine
Tanja Petnicki-Ocwieja et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
NOD2 contributes to cutaneous defense against Staphylococcus aureus through α-toxin-dependent innate immune activation
Petr Hruz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cardiac infiltration in early-onset sarcoidosis associated with a novel heterozygous mutation, G481D, in CARD15
Satoshi Okada et al.
RHEUMATOLOGY (2009)
A novel mutation in the NOD2 gene associated with Blau syndrome: a Norwegian family with four affected members
N. Milman et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2009)
The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
Kenichi Shimada et al.
PLOS PATHOGENS (2009)
NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis
Amit K. Pandey et al.
PLOS PATHOGENS (2009)
Bacterial Peptide Recognition and Immune Activation Facilitated by Human Peptide Transporter PEPT2
Peter W. Swaan et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-induced Tumorigenesis
Grace Y. Chen et al.
CANCER RESEARCH (2008)
Shared principles in NF-κB signaling
Matthew S. Hayden et al.
CELL (2008)
Muramylpeptide shedding modulates cell sensing of Shigella flexneri
Giulia Nigro et al.
CELLULAR MICROBIOLOGY (2008)
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
Osamu Hitotsumatsu et al.
IMMUNITY (2008)
The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to toll-like receptor ligands
Yun-Gi Kim et al.
IMMUNITY (2008)
Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity
Joao Gamelas Magalhaes et al.
JOURNAL OF IMMUNOLOGY (2008)
Common nonsynonymous polymorphisms in the NOD2 gene are associated with resistance or susceptibility to tuberculosis disease in African Americans
Celest M. Austin et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
Djahida Bouskra et al.
NATURE (2008)
Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen
Jess H. Leber et al.
PLOS PATHOGENS (2008)
GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors
Atsuko Fukazawa et al.
PLOS PATHOGENS (2008)
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
Thomas A. Kufer et al.
CELLULAR MICROBIOLOGY (2008)
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-κB activation
Mizuho Hasegawa et al.
EMBO JOURNAL (2008)
NOD1 gene E266K polymorphism is associated with disease susceptibility but not with disease phenotype or NOD2/CARD15 in Hungarian patients with Crohn's disease
T. Molnar et al.
DIGESTIVE AND LIVER DISEASE (2007)
NOD2 gene-associated pediatric granulomatous arthritis -: Clinical diversity, novel and recurrent mutations, and evidence of clinical improvement with interleukin-1 blockade in a Spanish cohort
Juan I. Arostegui et al.
ARTHRITIS AND RHEUMATISM (2007)
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome
Masafumi Myoishi et al.
CIRCULATION (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Prevalence of CARD15/NOD2 mutations in Caucasian healthy people
Jean-Pierre Hugot et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2007)
The NOD2-RICK complex signals from the plasma membrane
Patrick Lecine et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
John D. Rioux et al.
NATURE GENETICS (2007)
A role of lipophilic peptidoglycan-related molecules in induction of Nod1-mediated immune responses
Mizuho Hasegawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Modulation of Nod2-dependent NF-κB signaling by the actin cytoskeleton
Sylvie Legrand-Poels et al.
JOURNAL OF CELL SCIENCE (2007)
Regulation of Nod1-mediated signaling pathways
J. da Silva Correia et al.
CELL DEATH AND DIFFERENTIATION (2007)
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity
Jorg H. Fritz et al.
IMMUNITY (2007)
Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis
Peter Hofner et al.
HELICOBACTER (2007)
Bacterial Ligands generated in a phagosome are targets of the cytosolic innate immune system
Anat A. Herskovits et al.
PLOS PATHOGENS (2007)
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
Jong-Hwan Park et al.
JOURNAL OF IMMUNOLOGY (2007)
Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophages
Ronan Kapetanovic et al.
INFECTION AND IMMUNITY (2007)
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
Yen-Michael S. Hsu et al.
NATURE IMMUNOLOGY (2007)
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
Jochen Hampe et al.
NATURE GENETICS (2007)
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
Mark Windheim et al.
BIOCHEMICAL JOURNAL (2007)
Blau syndrome associated with a CARD15/NOD2 mutation
Bernadette Snyers et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2006)
hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides
Manfred G. Ismair et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2006)
Phagocytes containing a disease-promoting toll-like receptor/nod ligand are present in the brain during demyelinating disease in primates
Lizette Visser et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments
Mizuho Hasegawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes
Tsuyoshi Tanabe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
Murray C. H. Clarke et al.
NATURE MEDICINE (2006)
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis
Tomohiro Watanabe et al.
IMMUNITY (2006)
Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection
Philip Rosenstiel et al.
CELLULAR MICROBIOLOGY (2006)
TIR, CARD and PYRIN: three domains for an antimicrobial triad
C Werts et al.
CELL DEATH AND DIFFERENTIATION (2006)
Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor -: Critical regulators of β-defensins during helicobacter pylori infection
PK Boughan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
J Masumoto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
The emerging role of vascular smooth muscle cell apoptosis in atherosclerosis and plaque stability
Murray Clarke et al.
AMERICAN JOURNAL OF NEPHROLOGY (2006)
A role for Erbin in the regulation of Nod2-dependent NF-κB signaling
C McDonald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Synergistic effect of Nod1 and Nod2 Agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
H Tada et al.
INFECTION AND IMMUNITY (2005)
Identification of the critical residues involved in peptidoglycan detection by Nod1
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
T Ito et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
Gerben Ferwerda et al.
PLOS PATHOGENS (2005)
Induction and localization of NOD2 protein in human endothelial cells
HM Oh et al.
CELLULAR IMMUNOLOGY (2005)
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-κB activation in muramyl dipeptide recognition
N Barnich et al.
JOURNAL OF CELL BIOLOGY (2005)
Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults
S Weidinger et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2005)
Association of NOD1 polymorphisms with atopic eczema and related phenotypes
S Weidinger et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
A new CARD15 mutation in Blau syndrome
MM van Duist et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2005)
Murarnyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease
DA van Heel et al.
LANCET (2005)
Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease
DPB McGovern et al.
HUMAN MOLECULAR GENETICS (2005)
TLR signaling in the gut in health and disease
MT Abreu et al.
JOURNAL OF IMMUNOLOGY (2005)
NOD1 variation, immunoglobulin E and asthma
P Hysi et al.
HUMAN MOLECULAR GENETICS (2005)
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
KS Kobayashi et al.
SCIENCE (2005)
Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-10 processing
S Maeda et al.
SCIENCE (2005)
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation:: common genetic etiology with Blau syndrome
N Kanazawa et al.
BLOOD (2005)
Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease
L Visser et al.
JOURNAL OF IMMUNOLOGY (2005)
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
T Tanabe et al.
EMBO JOURNAL (2004)
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
JG Kim et al.
INFECTION AND IMMUNITY (2004)
Presence of a sporadic case of systemic granulomatosis syndrome with a CARD15 mutation
N Kanazawa et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae
B Opitz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression
J Wehkamp et al.
GUT (2004)
hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells
SR Vavricka et al.
GASTROENTEROLOGY (2004)
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
J Viala et al.
NATURE IMMUNOLOGY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocecal resection and are a risk factor for reoperation
C Büning et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2004)
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
M Chamaillard et al.
NATURE IMMUNOLOGY (2003)
Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan
SE Girardin et al.
SCIENCE (2003)
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
T Hisamatsu et al.
GASTROENTEROLOGY (2003)
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases
M Chamaillard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A role for innate immunity in type 1 diabetes?
H Beyan et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2003)
Host recognition of bacterial muramyl dipeptide mediated through NOD2
N Inohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
CARD15 gene mutations in sarcoidosis
M Schurmann et al.
EUROPEAN RESPIRATORY JOURNAL (2003)
In situ localization of Propionibacterium acnes DNA in lymph nodes from sarcoidosis patients by signal amplification with catalysed reporter deposition
T Yamada et al.
JOURNAL OF PATHOLOGY (2002)
Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora
S Fagarasan et al.
SCIENCE (2002)
Prospective study on the relationship between infections and multiple sclerosis exacerbations
D Buljevac et al.
BRAIN (2002)
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
AP Cuthbert et al.
GASTROENTEROLOGY (2002)
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
K Kobayashi et al.
NATURE (2002)
SopE and SopE2 from Salmonella typhimurium activate different sets of RhoGTPases of the host cell
A Friebel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
CARD15 mutations in Blau syndrome
C Miceli-Richard et al.
NATURE GENETICS (2001)
Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis
IA Schrijver et al.
BRAIN (2001)
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
SE Girardin et al.
EMBO REPORTS (2001)
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
C Wang et al.
NATURE (2001)
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
J Hampe et al.
LANCET (2001)
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
JP Hugot et al.
NATURE (2001)
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Y Ogura et al.
NATURE (2001)
Birth weight and childhood onset type 1 diabetes: population based cohort study
LC Stene et al.
BMJ-BRITISH MEDICAL JOURNAL (2001)
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB
Y Ogura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Human Nod1 confers responsiveness to bacterial lipopolysaccharides
N Inohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
