期刊
IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS
卷 39, 期 8, 页码 1635-1648出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TCAD.2019.2925354
关键词
Integrated circuit modeling; Solid modeling; Computational modeling; Chemicals; Valves; Layout; Oscillators; Autonomous flow control; chemofluidic membrane transistor (MIS-CVPT); chemofluidic oscillator; chemofluidic SR flip-flop; chemofluidic transistor (CVPT); chemofluidics; computer-aided design (CAD); continuous flow; design automation; functional design; lab-on-a-chip (LoC); microfluidics; modeling; schematic design; simulation; transient simulation
类别
资金
- German Research Foundation within the Cluster of Excellence Center for Advancing Electronics Dresden (Hydrogel-Based Microsystems) [GRK1865]
- European Social Fund
We present an approach to the schematic design and time-dependent simulation of microfluidic systems that are composed of basic components, such as pumps, channels, mixing junctions, and valves. For the schematic capture and the simulation, the Cadence Virtuoso design framework is employed, with the components modeled by Verilog-AMS. The pressures and flow rates are calculated with the help of the hydraulic analogy between electronics and fluidics. Signal flow quantities are used to express the flow of chemical concentration. Our focus is on systems employing chemofluidic transistors, i.e., hydrogel-based microvalves that facilitate autonomous flow control without the need for an external control unit. Our approach also covers layout editing by the use of programmed cells. The utility of the approach is exemplified by the successful top-down design of a chemofluidic oscillator circuit and by the functionally correct simulation of a chemofluidic SR flip-flop.
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