期刊
HUMAN REPRODUCTION
卷 35, 期 8, 页码 1732-1739出版社
OXFORD UNIV PRESS
DOI: 10.1093/humrep/deaa138
关键词
clinical trial design; time; medically assisted reproduction; time to live birth; statistical study design; outcomes; study design; trial design; endpoints
资金
- Merck KGaA (Darmstadt, Germany)
Time taken to achieve a live birth is an important consideration that is central to managing patient expectations during infertility treatment. However, time-related endpoints are not reported as standard in the majority of fertility-related clinical studies and there is no internationally recognized consensus definition for such endpoints. There is, therefore, a need for meaningful discussions around the selection of appropriate time-related treatment outcome measures for studies evaluating fertility treatments that will be relevant to diverse stakeholders (e.g. patients, healthcare professionals, clinical scientists, authorities and industry). Here, we provide a proposal for the evaluation of time-related outcome measures in fertility-related clinical studies, alongside associated definitions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据