4.2 Article

Development of a new comprehensive preoperative risk score for predicting 1-year mortality in patients with hip fracture: the HULP-HF score. Comparison with 3 other risk prediction models

期刊

HIP INTERNATIONAL
卷 31, 期 6, 页码 804-811

出版社

SAGE PUBLICATIONS LTD
DOI: 10.1177/1120700020947954

关键词

Hip fracture; mortality; risk prediction; scoring

资金

  1. Hospital La Paz Institute for Health Research, Madrid, Spain (IdiPAZ) (FONDA Cohort Study) [PI-1334]
  2. Spanish Ministry of Health, Fondo de Investigaciones Sanitarias, Instituto Carlos III [RETICEF RD 12/0043/0019]

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This study developed a new comprehensive preoperative risk score for predicting 1-year mortality in hip fracture patients, which showed slightly better predictive ability than existing scores.
Purpose: The aim of this study was to develop a new comprehensive preoperative risk score for predicting mortality during the first year after hip fracture (HF) and its comparison with 3 other risk prediction models. Methods: All patients admitted consecutively with a fragility HF during 1 year in a co-managed orthogeriatric unit at a university hospital were assessed and followed for 1 year. Factors independently associated with 1-year mortality were used to create the HULP-HF (Hospital Universitario La Paz - Hip Fracture) score. The predictive validity, discrimination and calibration of the HULP-HF score, the American Society of Anesthesiologists (ASA) scale, the abbreviated Charlson comorbidity index (a-CCI) and the Nottingham Hip Fracture score (NHFS) were compared. Discriminative performance was assessed using the area under the curve (AUC) and calibration by the Hosmer-Lemeshow goodness-of-fit-test. Results: 509 patients were included. 1-year mortality was 23.2%. The 8 independent mortality risk factors included in the HULP-HF score were age >85 years, baseline functional and cognitive impairment, low body mass index, heart disease, low hand-grip strength, anaemia on admission, and secondary hyperparathyroidism associated with vitamin D deficiency. The AUC was 0.79 in the HULP-HF score, 0.66 in the NHFS, 0.61 in the abbreviated CCI and 0.59 in the ASA scale. The HULP-HF score, the NHFS and the abbreviated CCI all presented good levels of calibration (p > 0.05). Conclusions: The HULP-HF score has a predictive capacity for 1-year mortality in HF patients slightly superior to that of other previously existing scores.

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