期刊
FUTURE ONCOLOGY
卷 16, 期 21, 页码 1549-1567出版社
FUTURE MEDICINE LTD
DOI: 10.2217/fon-2020-0151
关键词
epigenetics; epithelial-to-mesenchymal transition; melanoma; melanoma stem cells; mesenchymal-to epithelial transition; metastasis; tumor microenvironment
类别
This review provides an overview of the current understanding of the ontogeny and biology of melanoma stem cells in cutaneous malignant melanoma. This article also summarizes and evaluates the current knowledge of the underlying epigenetic mechanisms, the regulation of melanoma progress by the tumor microenvironment as well as the therapeutic implications and applications of these novel insights, in the setting of personalized medicine. Unraveling the complex ecosystem of cutaneous malignant melanoma and the interplay between its components, aims to provide novel insights into the establishment of efficient therapeutic strategies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据