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Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease
Gary P. Anderson
LANCET (2008)
Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin
Bertram Bleck et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2008)
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma
Mike Berry et al.
THORAX (2007)
Integrated breathing and relaxation training (the Papworth method) for adults with asthma in primary care: a randomised controlled trial
Elizabeth A. Holloway et al.
THORAX (2007)
Noneosinophilic asthma: A distinct clinical and pathologic phenotype
Pranab Haldar et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma
Stephen C. Lazarus et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2007)
Asthma control during the year after bronchial thermoplasty
Gerard Cox et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study
Surbhi Malhotra-Kumar et al.
LANCET (2007)
Innate immune activation in neutrophilic asthma and bronchiectasis
Jodie L. Simpson et al.
THORAX (2007)
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
Dominique M. A. Bullens et al.
RESPIRATORY RESEARCH (2006)
Role of deficient type III interferon-λ production in asthma exacerbations
Marco Contoli et al.
NATURE MEDICINE (2006)
Burying the dead - The impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease
R. William Vandivier et al.
CHEST (2006)
IL-17F sequence variant (His161Arg) is associated with protection against asthma and antagonizes wild-type IL-17F activity
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Low sputum eosinophils predict the lack of response to beclomethasone in symptomatic asthmatic patients
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CHEST (2006)
Determining asthma treatment by monitoring sputum cell counts:: effect on exacerbations
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EUROPEAN RESPIRATORY JOURNAL (2006)
Evidence of a role of tumor necrosis factor α in refractory asthma
MA Berry et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Inflammatory subtypes in asthma: Assessment and identification using induced sputum
JL Simpson et al.
RESPIROLOGY (2006)
An increase in bronchial responsiveness is associated with continuing or restarting smoking
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Diminished lipoxin biosynthesis in severe asthma
BD Levy et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
In vivo evaluation of the effectiveness of bronchial thermoplasty with computed tomography
RH Brown et al.
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Severe asthma treatment: need for characterising patients
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LANCET (2005)
Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment):: INNOVATE
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ALLERGY (2005)
Asthma, airway inflammation and treatment in elite athletes
I Helenius et al.
SPORTS MEDICINE (2005)
Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced
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GENES AND IMMUNITY (2004)
Asthma and cigarette smoking
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EUROPEAN RESPIRATORY JOURNAL (2004)
TL1A synergizes with IL-12 and IL-18 to enhance IFN-γ production in human T cells and NK cells
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JOURNAL OF IMMUNOLOGY (2004)
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease
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JOURNAL OF IMMUNOLOGY (2003)
Systematic assessment of difficult-to-treat asthma
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EUROPEAN RESPIRATORY JOURNAL (2003)
Predictors of therapy resistant asthma: outcome of a systematic evaluation protocol
LG Heaney et al.
THORAX (2003)
Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine
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RESPIRATORY MEDICINE (2003)
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial
RH Green et al.
LANCET (2002)
Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
RH Green et al.
THORAX (2002)
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4
BD Levy et al.
NATURE MEDICINE (2002)
Accuracy of eosinophils and eosinophil cationic protein to predict steroid improvement in asthma
RJ Meijer et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2002)
Lipoxins are potential endogenous antiinflammatory mediators in asthma
C Bonnans et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study
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LANCET (2002)
Eosinophilic bronchitis: clinical manifestations and implications for treatment
PG Gibson et al.
THORAX (2002)
Occupational asthma due to low molecular weight agents: eosinophilic and non-eosinophilic variants
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THORAX (2002)
Heterogeneity of airway inflammation in persistent asthma - Evidence of neutrophilic inflammation and increased sputum interleukin-8
PG Gibson et al.
CHEST (2001)
Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma
H Amayasu et al.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2000)
Non-invasive markers of airway inflammation as predictors of oral steroid responsiveness in asthma
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THORAX (2000)
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