4.7 Review

Dietary habits, lipoprotein metabolism and cardiovascular disease: From individual foods to dietary patterns

期刊

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 61, 期 10, 页码 1651-1669

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2020.1764487

关键词

Mediterranean diet; low-density lipoprotein cholesterol; healthy diet; cardiovascular disease; cardiometabolic risk factors

资金

  1. Ferrer
  2. Esteve
  3. Mylan
  4. Novartis
  5. GlaxoSmithKline
  6. Pfizer
  7. Janssen-Cilag
  8. Amgen
  9. Sanofi
  10. Angelini
  11. Astra Zeneca
  12. Boehringer Ingelheim
  13. Merck Sharp Dohme
  14. Novo Nordisk
  15. Servier
  16. WinMedica
  17. Bristol-Myers Squibb/Astra Zeneca
  18. Boehringer Ingelheim/Lilly

向作者/读者索取更多资源

Preventing unhealthy dietary habits and lack of physical activity is crucial in managing dyslipidemia, with scientific societies recommending adherence to healthy dietary patterns and increased exercise. These nutritional and lifestyle recommendations can prevent cardiovascular disease and effectively manage cardiometabolic risk factors.
Cardiovascular disease (CVD) remains the first cause of mortality in Western countries. Among cardiometabolic risk factors, dyslipidemia, and especially high low-density lipoprotein cholesterol (LDL-C) concentrations, have been extensively linked to the development and progression of atherosclerosis and to CVD events. Recent evidence has shown that the prevention of unhealthy dietary habits and sedentarism is crucial in the management of dyslipidemia. In this sense, a number of scientific societies recommend the adherence to certain healthy dietary patterns (DPs), such as the Mediterranean diet (MedDiet), the Dietary Approaches to Stop Hypertension (DASH), the Portfolio diet, the Vegetarian diet, the Nordic diet and low-carbohydrate diets, as well as increased physical activity between others. This nutritional and lifestyle advice could be adopted by government bodies and implemented in different health programs as a reliable way of providing health-care professionals with efficient tools to manage cardiometabolic risk factors and thus, prevent CVD. In this narrative review, we will discuss recent data about the effects of nutrition on dyslipidemia, mainly focusing on high LDL-C concentrations and other lipid particles related to atherogenic dyslipidemia such as triglycerides (TG) and non-high density lipoprotein cholesterol (non-HDL-C), that are related to CVD. On the other hand, we also comment on other cardiometabolic risk factors such as type 2 diabetes mellitus (T2DM), high blood pressure (HBP), inflammation and endothelial dysfunction. This review includes food groups as well as different healthy DPs.

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