期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 190, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.colsurfb.2020.110930
关键词
Multifunctional carbon dots; Antibacterial activity; Bioimaging; Bacterial discrimination
资金
- Jiangsu six category outstanding talent [2012-NY-031]
- Jiangsu province science and technology support plan [BE2015367]
- Jiangsu Science and Technology Plan [BE2019391]
- Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
Multifunctional carbon dots (CDs) present enormous potential in numerous applications and have attracted widespread attention for various applications in the biomedical field. Bacterial infection is a common health issue; the development of antibacterial materials with low toxicity and good biocompatibility is becoming more important. In this work, we synthesized a new type of nitrogen co-doped carbon dots-genipin covalent conjugate (N-CDs-GP) via hydrothermal methods. The microstructure and chemical composition of the N-CDs-GP were characterized. The biocompatibility, stability, antibacterial activity, and fluorescence performance of the N-CDsGP were assessed. The results revealed that N-CDs-GP possessed high biocompatibility, high light stability, and broad antibacterial activity. Additionally, selective Gram-positive bacterial imaging by N-CDs-GP provided a more rapid method of bacterial detection. The N-CDs-GP have the potential to be applied as bioimaging and antibacterial agents and for bacterial discrimination.
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