A Journey toSPSiOL, a New Type of Chiral Ligand Scaffold

We report the development of a class of chiral spirosilabiindane scaffoldsviaRh-catalyzed asymmetric double hydrosilation. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for preparation of various chiral ligands and catalysts, could be readily prepared on >10-gram scale using this protocol.