期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 26, 期 45, 页码 10222-10225出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.202002878
关键词
boron-mediated aglycon delivery; glycosphingolipids; glycosylation; terpioside B; total synthesis
资金
- JSPS KAKENHI [JP19H02724]
- SUNBOR Grant from the Suntory Foundation for Life Sciences
The first total synthesis of terpioside B (1) has been accomplished. Key steps include the stereoselective installments of a set of challenging 1,2-cis-glycosidic linkages. Thus, alpha(1,4)-linkedd-galactoside was effectively constructed from a 1,2-anhydrogalactose donor and an unprotected 1,6-anhydrogalactose acceptor by using a boron-mediated aglycon delivery (BMAD) method. In addition, alpha-l-fucofuranosides were stereoselectively and simultaneously constructed by remote group-assisted 1,2-cis-alpha-stereoselective glycosylations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据