4.6 Article

Deoxygenation of Epoxides with Carbon Monoxide

期刊

CHEMISTRY-A EUROPEAN JOURNAL
卷 26, 期 46, 页码 10634-10640

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.202002651

关键词

deoxygenation; epoxides; homogeneous catalysis; iridium; pincer ligands

资金

  1. MWK-BW

向作者/读者索取更多资源

The use of carbon monoxide as a direct reducing agent for the deoxygenation of terminal and internal epoxides to the respective olefins is presented. This reaction is homogeneously catalyzed by a carbonyl pincer-iridium(I) complex in combination with a Lewis acid co-catalyst to achieve a pre-activation of the epoxide substrate, as well as the elimination of CO(2)from a gamma-2-iridabutyrolactone intermediate. Especially terminal alkyl epoxides react smoothly and without significant isomerization to the internal olefins under CO atmosphere in benzene or toluene at 80-120 degrees C. Detailed investigations reveal a substrate-dependent change in the mechanism for the epoxide C-O bond activation between an oxidative addition under retention of the configuration and an S(N)2 reaction that leads to an inversion of the configuration.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据