Bronsted Acid-Catalysed Dehydrative Substitution Reactions of Alcohols

The direct, catalytic dehydrative substitution of alcohols is a challenging, yet highly desirable process in the development of more sustainable approaches to organic chemistry. This review outlines recent advances in Bronsted acid-catalysed dehydrative substitution reactions for C-C, C-O, C-N and C-S bond formation. The wide range of processes that are now accessible using simple alcohols as the formal electrophile are highlighted, while current limitations and therefore possible future directions for research are also discussed.

Automated summary

This review outlines recent advances in Bronsted acid-catalysed dehydrative substitution reactions for C-C, C-O, C-N and C-S bond formation. It highlights the wide range of processes accessible using simple alcohols as the formal electrophile, while discussing current limitations and possible future research directions.