期刊
CELL STEM CELL
卷 27, 期 2, 页码 192-194出版社
CELL PRESS
DOI: 10.1016/j.stem.2020.07.010
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资金
- NCI NIH HHS [P50 CA211015] Funding Source: Medline
- NIGMS NIH HHS [T32 GM008042] Funding Source: Medline
Senescence is a critical factor in several diseases, yet senolytic therapies targeting senescent cells remain hindered by lack of specificity. In the June issue of Nature, Amor et al. (2020) develop chimeric antigen receptor (CAR)-T cells targeting uPAR, a novel senescent-cell marker, to treat liver adenocarcinoma and liver fibrosis.
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