相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Roles of Fibroblast Activation Protein and Hepatocyte Growth Factor Expressions in Angiogenesis and Metastasis of Gastric Cancer
Li-Ming Gao et al.
PATHOLOGY & ONCOLOGY RESEARCH (2019)
Targeting cardiac fibrosis with engineered T cells
Haig Aghajanian et al.
NATURE (2019)
Fibroblast activation protein- promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways
Jun Jia et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Toxicological profile and safety pharmacology of a single dose of fibroblast activation protein--based doxorubicin prodrug: in-vitro and in-vivo evaluation
Sichao Huang et al.
ANTI-CANCER DRUGS (2018)
Polyphyllin I inhibits gastric cancer cell proliferation by downregulating the expression of fibroblast activation protein alpha (FAP) and hepatocyte growth factor (HGF) in cancer-associated fibroblasts
Ruizeng Dong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice
Pratiksha Gulati et al.
CLINICAL CANCER RESEARCH (2018)
Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
Thomas Karsten Kilvaer et al.
PLOS ONE (2018)
Chimeric antigen receptor T cell therapy for non-Hodgkin lymphoma
Armin Ghobadi
CURRENT RESEARCH IN TRANSLATIONAL MEDICINE (2018)
The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition
Zuzana Kahounova et al.
CYTOMETRY PART A (2018)
Low expression of miR-30a-5p induced the proliferation and invasion of oral cancer via promoting the expression of FAP
Peng Ruan et al.
BIOSCIENCE REPORTS (2018)
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis
Marian C. Okondo et al.
NATURE CHEMICAL BIOLOGY (2017)
A novel FAPa-basedZ-Gly-Pro epirubicin prodrug for improving tumor-targeting chemotherapy
Jun Wang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Effects of the fibroblast activation protein inhibitor, PT100, in a murine model of pulmonary fibrosis
Christine Egger et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Changes in concentrations of circulating fibroblast activation protein alpha are associated with myocardial damage in patients with acute ST-elevation MI
Jochen Tillmanns et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2017)
Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents
Minfeng Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Biomarkers in Tumor Microenvironment? Upregulation of Fibroblast Activation Protein-α Correlates with Gastric Cancer Progression and Poor Prognosis
Mengmou Hu et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2017)
Fibroblast Activation Protein-alpha-Positive Fibroblasts Promote Gastric Cancer Progression and Resistance to Immune Checkpoint Blockade
Xuyang Wen et al.
ONCOLOGY RESEARCH (2017)
Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease
Shirley Uitte de Willige et al.
PLOS ONE (2017)
The prognostic significance of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma
Hyunjin Park et al.
TUMOR BIOLOGY (2017)
Heterogeneity of molecular forms of dipeptidyl peptidase-IV and fibroblast activation protein in human glioblastomas
Ivana Matrasova et al.
BIOMEDICAL PAPERS-OLOMOUC (2017)
Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma
Albert Lo et al.
JCI INSIGHT (2017)
FAP positive fibroblasts induce immune checkpoint blockade resistance in colorectal cancer via promoting immunosuppression
Lingling Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Circulating FGF21 proteolytic processing mediated by fibroblast activation protein
Eugene Y. Zhen et al.
BIOCHEMICAL JOURNAL (2016)
Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
Ming-Hui Fan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Expression of cancer-associated fibroblast-related proteins differs between invasive lobular carcinoma and invasive ductal carcinoma
Cheol Keun Park et al.
BREAST CANCER RESEARCH AND TREATMENT (2016)
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling
Xuguang Yang et al.
CANCER RESEARCH (2016)
Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21
Diana Ronai Dunshee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Targeting of cancer-associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment
Minmin Li et al.
MOLECULAR MEDICINE REPORTS (2016)
Fibroblast activation protein alpha is expressed by transformed and stromal cells and is associated with mesenchymal features in glioblastoma
Petr Busek et al.
TUMOR BIOLOGY (2016)
Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression
Claudia Sorrentino et al.
ONCOTARGET (2016)
Fibroblast activation protein (FAP) as a novel metabolic target
Miguel Angel Sanchez-Garrido et al.
MOLECULAR METABOLISM (2016)
Luciferase expression is driven by the promoter of fibroblast activation protein-α in murine pulmonary fibrosis
Li Wenlong et al.
BIOTECHNOLOGY LETTERS (2015)
Fibroblast activation protein-α-expressing fibroblasts promote the progression of pancreatic ductal adenocarcinoma
Tomoya Kawase et al.
BMC GASTROENTEROLOGY (2015)
Differential expression of cancer-associated fibroblast-related proteins according to molecular subtype and stromal histology in breast cancer
Sung Yeon Park et al.
BREAST CANCER RESEARCH AND TREATMENT (2015)
Lower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity
K. H. Williams et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2015)
Plasma levels of soluble fibroblast activation protein in arterial thrombosis; determinants and cleavage of its substrate alpha-2-antiplasmin
Shirley Uitte de Willige et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)
Fibroblast activation protein alpha expression identifies activated fibroblasts after myocardial infarction
Jochen Tillmanns et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti-Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis
Peter Laverman et al.
JOURNAL OF NUCLEAR MEDICINE (2015)
Expression of cancer-associated fibroblast-related proteins in adipose stroma of breast cancer
Yoon Yang Jung et al.
TUMOR BIOLOGY (2015)
Deficiency of fibroblast activation protein alpha ameliorates cartilage destruction in inflammatory destructive arthritis
Stefan Waeldele et al.
ARTHRITIS RESEARCH & THERAPY (2015)
Expression levels of seprase/FAP and DPPIV/CD26 in epithelial ovarian carcinoma
Mengzhen Zhang et al.
ONCOLOGY LETTERS (2015)
Fibroblast Activation Protein Overexpression and Clinical Implications in Solid Tumors: A Meta-Analysis
Fang Liu et al.
PLOS ONE (2015)
A whole-cell tumor vaccine modified to express fibroblast activation protein induces antitumor immunity against both tumor cells and cancer-associated fibroblasts
Meihua Chen et al.
SCIENTIFIC REPORTS (2015)
FAP-α (Fibroblast activation protein-α) is involved in the control of human breast cancer cell line growth and motility via the FAK pathway
Jun Jia et al.
BMC CELL BIOLOGY (2014)
miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Chang Gong et al.
CANCER RESEARCH (2014)
Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas
Dongsheng Yue et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2014)
Extended Structure Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycy1-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)
Koen Jansen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Fibroblast Activation Protein (FAP) Is Essential for the Migration of Bone Marrow Mesenchymal Stem Cells through RhoA Activation
Kuei-Min Chung et al.
PLOS ONE (2014)
Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma
H. Wang et al.
CELL DEATH & DISEASE (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Tumoral Immune Suppression by Macrophages Expressing Fibroblast Activation Protein-α and Heme Oxygenase-1
James N. Arnold et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs
Fiona M. Keane et al.
FEBS OPEN BIO (2014)
Over-expression of fibroblast activation protein alpha increases tumor growth in xenografts of ovarian cancer cells
Lijuan Yang et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2013)
Fibroblast activation protein-alpha promotes ovarian cancer cell proliferation and invasion via extracellular and intracellular signaling mechanisms
WeiWei Yang et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2013)
Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens
Jiping Zhang et al.
FASEB JOURNAL (2013)
Circulating concentrations of fibroblast activation protein α in apparently healthy individuals and patients with acute coronary syndrome as assessed by sandwich ELISA
Jochen Tillmanns et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
Edward W. Roberts et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
Eric Tran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Increased N-terminal cleavage of alpha-2-antiplasmin in patients with liver cirrhosis
S. Uitte De Willige et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)
Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells
Petra C. Schuberth et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
Antitumor Effects of Chimeric Receptor Engineered Human T Cells Directed to Tumor Stroma
Sunitha Kakarla et al.
MOLECULAR THERAPY (2013)
Val-BoroPro Accelerates T Cell Priming via Modulation of Dendritic Cell Trafficking Resulting in Complete Regression of Established Murine Tumors
Meghaan P. Walsh et al.
PLOS ONE (2013)
A Vaccine That Co-Targets Tumor Cells and Cancer Associated Fibroblasts Results in Enhanced Antitumor Activity by Inducing Antigen Spreading
Stephen Gottschalk et al.
PLOS ONE (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis
Maria L. Wikberg et al.
TUMOR BIOLOGY (2013)
Targeting Inhibition of Fibroblast Activation Protein-α and Prolyl Oligopeptidase Activities on Cells Common to Metastatic Tumor Microenvironments
Victoria J. Christiansen et al.
NEOPLASIA (2013)
Radioimmunotherapy of Fibroblast Activation Protein Positive Tumors by Rapidly Internalizing Antibodies
Eliane Fischer et al.
CLINICAL CANCER RESEARCH (2012)
Fibroblast activation protein regulates tumor-associated fibroblasts and epithelial ovarian cancer cells
Dongmei Lai et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Combination of a Bispecific Antibody and Costimulatory Antibody-Ligand Fusion Proteins for Targeted Cancer Immunotherapy
Nora Hornig et al.
JOURNAL OF IMMUNOTHERAPY (2012)
Expression of fibroblast activation protein in human pancreatic adenocarcinoma and its clinicopathological significance
Min Shi et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2012)
Expression and role of the cell surface protease seprase/fibroblast activation protein-α (FAP-α) in astroglial tumors
Rolf Mentlein et al.
BIOLOGICAL CHEMISTRY (2011)
FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
Hyung-Ok Lee et al.
BMC CANCER (2011)
Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion
Yuan Zhang et al.
CANCER LETTERS (2011)
Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions
Yan Huang et al.
CLINICAL & EXPERIMENTAL METASTASIS (2011)
Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma
Xing Hua et al.
DIAGNOSTIC PATHOLOGY (2011)
Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata
Chad E. Brokopp et al.
EUROPEAN HEART JOURNAL (2011)
Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α
Fiona M. Keane et al.
FEBS JOURNAL (2011)
Fibroblast Activation Protein Expression in Crohn's Disease Strictures
Laura Rovedatti et al.
INFLAMMATORY BOWEL DISEASES (2011)
Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate
Chih-Hsiang Huang et al.
JOURNAL OF BIOCHEMISTRY (2011)
Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option
Kirstin Dienus et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2010)
Inhibition of Fibroblast Activation Protein and Dipeptidylpeptidase 4 Increases Cartilage Invasion by Rheumatoid Arthritis Synovial Fibroblasts
Caroline Ospelt et al.
ARTHRITIS AND RHEUMATISM (2010)
Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model
Yuan Wen et al.
CANCER SCIENCE (2010)
Pediatric Phase I Trial Design Using Maximum Target Inhibition as the Primary Endpoint
Holly Meany et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
TWIST1 promotes invasion through mesenchymal change in human glioblastoma
Svetlana A. Mikheeva et al.
MOLECULAR CANCER (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma
Robert M. Eager et al.
BMC CANCER (2009)
Inhibitor of DASH proteases affects expression of adhesion molecules in osteoclasts and reduces myeloma growth and bone disease
Angela Pennisi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Phase II Trial of Talabostat and Docetaxel in Advanced Non-small Cell Lung Cancer
R. M. Eager et al.
CLINICAL ONCOLOGY (2009)
TGF-β-induced fibroblast activation protein expression, fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM
He Chen et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2009)
Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells
Alanna Kennedy et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
Angelica M. Santos et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Molecular characterization of human breast tumor vascular cells
Rajendra Bhati et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites
Saurabh Aggarwal et al.
BIOCHEMISTRY (2008)
Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer
Jennifer M. Bailey et al.
CLINICAL CANCER RESEARCH (2008)
Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma
Steven J. Cohen et al.
PANCREAS (2008)
Expression of seprase in effusions from patients with epithelial ovarian carcinoma
Zhang Meng-zhen et al.
CHINESE MEDICAL JOURNAL (2007)
Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization
Sarah A. Meadows et al.
BIOCHEMISTRY (2007)
Clinical implications of fibroblast activation protein in patients with colon cancer
Leonard R. Henry et al.
CLINICAL CANCER RESEARCH (2007)
Effect of fibroblast activation protein and α2-antiplasmin cleaving enzyme on collagen types I, III, and IV
Victoria J. Christiansen et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
Markus Loeffler et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices
Giulio Ghersi et al.
CANCER RESEARCH (2006)
Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival
Y Ge et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly2-Pro1-cleaving specificity
CY Edosada et al.
FEBS LETTERS (2006)
Fibroblast activation protein:: a serine protease expressed at the remodeling interface in idiopathic pulmonary flbrosis
PS Acharya et al.
HUMAN PATHOLOGY (2006)
Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein
KN Lee et al.
BLOOD (2006)
Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis
JM Milner et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes
Stefan Bauer et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein α
K Aertgeerts et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PT-100, a small molecule dipeptidyl peptidase inhibitorg has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism
S Adams et al.
CANCER RESEARCH (2004)
FAPα, a surface peptidase expressed during wound healing, is a tumor suppressor
T Ramirez-Montagut et al.
ONCOGENE (2004)
Purification, identification and characterisation of seprase from bovine serum
PJ Collins et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
A novel plasma proteinase potentiates α2-antiplasmin inhibition of fibrin digestion
KN Lee et al.
BLOOD (2004)
The expression of a type II transmembrane serine protease (seprase) in human gastric carcinoma
Y Mori et al.
ONCOLOGY (2004)
Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies
B Jones et al.
BLOOD (2003)
Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis
RT Aimes et al.
THROMBOSIS AND HAEMOSTASIS (2003)
Fibroblast activation protein: Differential expression and serine protease activity in reactive stromal fibroblasts of melanocytic skin tumors
MA Huber et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2003)
Stromal antigen targeting by a humanised monoclonal antibody:: An early phase II trial of sibrotuzamab in patients with metastatic colorectal cancer
RD Hofheinz et al.
ONKOLOGIE (2003)
Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells
JD Goodman et al.
CLINICAL & EXPERIMENTAL METASTASIS (2003)
Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer
K Okada et al.
ONCOLOGY (2003)
Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes:: dependence on β1 integrins and the cytoskeleton
VV Artym et al.
CARCINOGENESIS (2002)
Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection
MT Levy et al.
LIVER (2002)
Expression, purification, and kinetic characterization of full-length human fibroblast activation protein
SX Sun et al.
PROTEIN EXPRESSION AND PURIFICATION (2002)
Construction of a bispecific single chain antibody for recruitment of cytotoxic T cells to the tumour stroma associated antigen fibroblast activation protein
T Wüest et al.
JOURNAL OF BIOTECHNOLOGY (2001)
Targeted disruption of mouse fibroblast activation protein
J Niedermeyer et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Identification of an alternatively spliced seprase mRNA that encodes a novel intracellular isoform
LA Goldstein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)