期刊
BIORESOURCE TECHNOLOGY
卷 308, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2020.123319
关键词
Biorefinery; Lignocellulosic biomass; Inhibitory compounds; Toxic effect; Aspergillus terreus NRRL 1960
资金
- National Council of Technological and Scientific Development (CNPq) [442271/2017-4]
- Coordination for the Improvement of Higher Education Personnel (CAPES), PNPD Program
The ability to produce second-generation itaconic acid by Aspergillus terreus, and the inhibitory effects of hydrolysis by-products on the fermentation were evaluated by cultivation in a synthetic medium containing components usually present in a real hydrolysate broth from lignocellulosic biomasses. The results showed that A. terreus NRRL 1960 can produce itaconic acid and consume xylose completely, but the conversion is less than the fermentation using only glucose. In addition, compared to fermentation of glucose, or even xylose, the mix of both sugars resulted in a lower itaconic acid yield. In the inhibitory test, the final itaconic acid titer was reduced by acetic acid, furfural, and 5-hydroxymethylfurfural concentrations of, respectively, 188, 175, and 700 mg L-1 . However, the presence of any amount of acetic acid proved to be detrimental to itaconic acid production. This research sheds some light on doubts about the biorefinery implementation of itaconic acid production.
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