CONAN: a web application to detect specificity determinants and functional sites by amino acids co-variation network analysis

A Summary: CONAN is a web application developed to detect specificity determinants and function-related sites by amino acids co-variation networks analysis, emphasizing local coevolutionary constraints. The software allows the characterization of structurally and functionally relevant groups of residues and their relationship with subsets of sequences by automatic cross-referencing with GO terms, UniprotKb annotations and INTERPRO.

Automated summary

CONAN is a web application developed for detecting specificity determinants and function-related sites through amino acids co-variation networks analysis, with a focus on local coevolutionary constraints. The software enables the characterization of structurally and functionally relevant residue groups by automatically cross-referencing with GO terms, UniprotKb annotations, and INTERPRO.