期刊
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
卷 69, 期 -, 页码 74-84出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2020.05.005
关键词
Progesterone; Luteal phase support; Assisted reproductive technology; Pregnancy; Live birth
资金
- Spanish Ministry of Education, Culture and Sport
- Finox
Progesterone is the main hormone in the luteal phase. It plays a key role in preparing the uterus for a possible pregnancy, and in maintaining it after it has occurred. In assisted reproduction treatments, there is usually a luteal phase deficiency, so it is necessary to supplement this critical phase to obtain the best results, not only of implantation but also of ongoing pregnancy. Among all the available options, exogenously administered progestogens are the most used, as they have proven their efficacy and safety. This review will address the most relevant aspects of luteal phase support with progesterone in the different scenarios an embryo transfer can be performed, such as the stimulated cycle, the artificial cycle, or the natural cycle. Although there is no evidence of the perfect protocol for all patients, recent studies point to the need of individualizing luteal phase support according to the needs of each patient. (c) 2020 Published by Elsevier Ltd.
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