期刊
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
卷 16, 期 5, 页码 E216-E222出版社
WILEY
DOI: 10.1111/ajco.13368
关键词
diagnostic accuracy; histopathology; magnetic resonance imaging staging; rectal cancer
类别
资金
- National Natural Science Foundation of China [81874217, 81703028]
- Young Medical Key Talents of Jiangsu Province [QNRC2016572]
- Priority Academic Program Development of Jiangsu Higher Education Institutions [JX10231801]
- Suzhou Clinical Medical Expert Team [SZYJTD201824]
Background To determine the diagnostic accuracy of preoperative T/N stage with magnetic resonance imaging (MRI) in lower and middle rectal cancer patients and the impacts on clinical decision-making. Patients and methods A total of 211 patients were recruited from October 2015 to March 2017 in this retrospective study. High-resolution MRI was performed within 2 weeks before surgery. Histopathologic results were evaluated for the postoperative T/N stage and the diagnostic accuracy of MRI was assessed according to the postoperative histopathologic results. The accuracy, sensitivity, specificity, positive predictive value and negative predictive value were evaluated for T/N staging and kappa values were used to evaluate MRI consistent analysis compared with postoperative histopathologic staging. Results The overall MRI diagnostic accuracy was 79.62% for T1-4 staging and 54.50% for N0-2 staging. The kappa values were 0.619 and 0.255 for T1-4 and N0-2 staging, respectively. The diagnostic accuracy of MRI for treatment decision-making was 80.57%. Conclusion MRI allows a highly accurate preoperative assessment of T stage but only a fairly accurate preoperative assessment of N stage for rectal cancer. The diagnostic accuracy of MRI for treatment decision-making is promising, but additional studies are needed to validate these findings in a larger sample size from multiple centers.
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