期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 64, 期 9, 页码 -出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00643-20
关键词
antifungal susceptibility; dematiaceous fungi; isavuconazole; ravuconazole
资金
- National Natural Science Foundation of China [81972949]
- scientific and technological innovation projects of medicine and health of the Chinese Academy of Medical Sciences [2016-I2M-3-021]
- basic scientific research fund projects of the Chinese Academy of Medical Sciences [2018PT31013]
- National Science and Technology Major Project [2018ZX10734404]
- Young Teacher Foundation [3332018121]
The in vitro activities of 11 antifungals against 84 dematiaceous fungi were tested. For most tested fungal species, the MIC values of ravuconazole and isavuconazole were lower than those obtained with itraconazole, voriconazole, and posaconazole. Ravuconazole and isavuconazole appear to be more efficient against most dematiaceous fungal infections than the other triazoles. However, some pigmented fungi, such as Bipolaris spicifera and Veronaea botryosa, remain more susceptible to other triazoles or to echinocandins.
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